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Ricky Antonia (Al Baldwin lab) published a paper titled “IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells“ in Science Signaling (DOI: 10.1126/scisignal.aan5850). Image: IKK regulates basal AMPK Thr172 phosphorylation in cell lines; see article for details. Please see our page on Publications by...

Lauren Donoghue (Samir Kelada lab) was awarded an NRSA F31 fellowship from the National Heart, Lung, and Blood Institute.Lauren’s project is titled, “Genetic and Longitudinal Analysis of Airway Remodeling.” Please also see our page on Grants to GMB Students.

Kristi Schaefer (Mark Peifer lab) published an article titled “Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo” in PLOS Genetics (DOI:10.1371/journal.pgen.1007339). Image: Accumulation of Arm, axin, and Wg in聽Drosophila embryos; click to enlarge; see article for...

Congratulations to Nicole Arruda (Jill Dowen lab), who was awarded a Graduate Research Fellowship from the National Science Foundation.聽 Nicole’s project is titled, “Cis-Regulatory Elements Connect Gene Expression and Genome Organization.” Please also see our page on Grants to GMB Students.

Congratulations to Allyson Roberts (Bob Goldstein lab), who was awarded a Graduate Research Fellowship from the National Science Foundation.聽 Allyson’s project is titled, “Investigating the relationship between cell fate specification and shape change during development.” Please also see our page on Grants to GMB Students.

Congratulations to Matt Niederhuber (Dan McKay lab), who was awarded a Graduate Research Fellowship from the National Science Foundation.聽 Matt’s project is titled, “Temporal Control of Enhancer Decommissioning.” Please also see our page on Grants to GMB Students.

Michelle Hoffner (Shehzad Sheikh lab) and Dean Nehama (Barbara Savoldo lab) were inducted into the Frank Porter Graham Graduate and Professional Student Honor Society. This award recognizes “outstanding service provided to the University and community by graduate and professional students.” Please also see our page on Awards to GMB Students.

Kelsey Gray (Greg Matera lab) published a paper titled “Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron“ in Molecular Biology of the Cell (DOI: 10.1091/mbc.E17-11-0627). Image: Proposed model of SMN as a substrate of SCFSlmb E3 ubiquitin ligase; see article for details. Please see...

Blake Albright (Aravind Asokan lab) published an article titled “Mapping the Structural Determinants Required for AAVrh.10 Transport across the Blood-Brain Barrier” in Molecular Therapy (DOI: 10.1016/j.ymthe.2017.10.017). Image: Mapping a minimal AAVrh.10 footprint for crossing the blood-brain barrier; see article for details.   Please see our page on Publications by GMB...

Morgan Brady (Jeff Sekelsky lab) published an article titled “Loss of Drosophila Mei-41/ATR Alters Meiotic Crossover Patterning” in Genetics (DOI: 10.1534/genetics.117.300634). Image: Changes in crossover interference in ATR mutants; see article for details. Please see our page on Publications by GMB Students for more.

Tamara Roman (Karen Mohlke lab) published a review titled “Functional genomics and assays of regulatory activity detect mechanisms at loci for lipid traits and coronary artery disease” in Current Opinion in Genetics and Development聽(DOI: 10.1016/j.gde.2018.02.004). Image: Chromatin regulatory annotations predict rs10872142 is located within an enhancer; see article for details....

Luke Laudermilk (Samir Kelada lab) published a paper titled “Differential regulation of Zfp30 expression in murine airway epithelia through altered binding of ZFP148 to rs51434084” in G3: Genes|Genomes|Genetics (DOI: 10.1534/g3.117.300507). Image: Differential ZFP148 binding demonstrated by electrophoretic mobility supershift assay super-shifting (click to enlarge); see article for details. Please see...