黑料网

Megan Justice (Jill Dowen lab) was selected to participate in the Yale University Ciencia Initiative. Throughout 2019, Megan will participate in a program designed 鈥渢o expand access to scientific knowledge, experiences, and careers among communities or populations traditionally underrepresented in, or underserved by, the scientific enterprise.鈥�

Tim Dinh (Praveen Sethupathy lab) published an article titled “MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma” in Cellular and Molecular Gastroenterology and Hepatology. Image: miR-375 is a candidate master regulator of cancer pathways in FLC; click to enlarge; see article for details.) Please see our page on Publications...

Kristi Schaefer (recent graduate of Mark Peifer lab) published a review article titled “Wnt/Beta-Catenin Signaling Regulation and a Role for Biomolecular Condensates” in Developmental Cell (DOI:10.1016/j.devcell.2019.01.025). Image: textbook model of Wnt signalling; click to enlarge; see article for details.) Please see our page on Publications by GMB Students for more.

Lauren Donoghue (Samir Kelada lab) received the Lorraine Flaherty Award for outstanding oral presentation in the Trainee Symposium at the 32nd International Mammalian Genome Conference in Puerto Rico. As winner of that award, Lauren was selected to give her presentation again in the main conference section, where she聽again was selected...

Talia Hatkevich (Jeff Sekelsky lab) was selected for a DeLill Nasser Award for Professional Development in Genetics from the Genetics Society of America. Talia will use the award to travel to the Drosophila Research Conference where she has been selected to give a talk. Please also see our page on...

Pedro Pozo (Jean Cook lab) published an聽 review article titled, “Cdt1 variants reveal unanticipated aspects of interactions with Cyclin/CDK and MCM important for normal genome replication” in Molcular Biology of the Cell (DOI: 10.1091/mbc.E18-04-0242).聽 Image: Flow cytometry profiles of cells with Ctd1 mutations; see paper for details.   Please see...

Robin Armstrong and Taylor Penke (Bob Duronio lab) published a paper titled “Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila“ in Genome Research (DOI: 10.1101/gr.239913.118). Image: Replication timing in a 5 Mb region of pericentric heterochromatin in wild-type and Histone H3K9R mutants; see article...

Rowan Beck (Praveen Sethupathy and Mirek Styblo labs) published an article titled, “Circulating miRNAs Associated with Arsenic Exposure” in Environmental Science and Technology (DOI: 10.1021/acs.est.8b06457).聽 Image: Outline of experimental strategy. See paper for details.   Please see our page on Publications by GMB Students for more.

Matt Tegowski (Al Baldwin lab) published a paper titled “Thioridazine inhibits self-renewal in breast cancer cells via DRD2-dependent STAT3 inhibition, but induces a G1 arrest independent of DRD2s“ in Journal of Biological Chemistry (DOI: 10.1074/jbc.RA118.003719). Image: Model describing mechanism of thioridazine effects on triple-negative breast cancer cell lines; see article...

Lauren Donoghue (Samir Kelada lab) received the Jo Rae Wright Young Investigator of the Year Award at the FASEB Lung Epithelium in Health and Disease聽conference.聽This award is聽given to one trainee in recognition of outstanding work described in an oral presentation. Lauren’s presentation was entitled “Genetic Analysis of Secreted Airway Mucins...

Carrie Wilczewski (Frank Conlon lab) published a paper titled “CHD4 and the NuRD complex directly control cardiac sarcomere formation“ in Proceedings of the National Academy of Sciences of the USA (DOI: 10.1073/pnas.1722219115). Image: Scanning electron micrographs of Chd4螖flox/螖flox and control hearts; see article for details. Please see our page on...

Anna Chiarella (Nate Hathaway lab) published a paper titled “Cavitation enhancement increases the efficiency and consistency of chromatin fragmentation from fixed cells for downstream quantitative applications“ in Biochemistry (DOI: 10.1021/acs.biochem.8b00075). Image: 16-fold increase in efficiency of sonication when nanodroplets are used; see article for details. Please see our page on...