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Amanda Raimer (Greg Matera lab) published an article titled “Temperature-sensitive spinal muscular atrophy-causing point mutations lead to SMN instability, locomotor defects and premature lethality in Drosophila” in Disease Models and Mechanisms. (DOI: 10.1242/dmm.04330)聽 Image: Temperature-sensitive protein stability in SMN Tudor domain mutants. Please see our page on Publications by GMB...

Rachel Cherney (Mauro Calabrese lab) received an NRSA F31 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The title of Rachel’s project is “Regulation of Polycomb by long noncoding RNAs during pre-implantation development.”   Please see our page on Grants to GMB Students for...

Nisitha Sengottuvel (Chad Pecot lab) was awarded an NRSA F30 fellowship from NIH’s National Cancer Institute. Nisitha’s project is titled “The role of SPON1 expressing inflammatory monocytes in promoting lung cancer metastasis.” Please also see our page on Grants to GMB Students.

Congratulations to Gabby Gentile (Jimena Giudice lab), who was awarded a Graduate Research Fellowship from the National Science Foundation.   Please also see our page on Grants to GMB Students.

Congratulations to the following GMB students who were recognized with Honorable Mention in the Graduate Research Fellowship competition from the National Science Foundation: Jeanne-Marie McPherson (Bob Duronio and Dan McKay labs) Victoria Parsons (Karen Mohlke lab) Alexis Stutzman (Jill Dowen and Dan McKay labs) Carolyn Turcotte (Jeff Sekelsky lab)

Meng Cheng (Yue Xiong lab) published a paper titled “Discovery of potent and selective epidermal growth factor receptor (EGFR) bifunctional small-molecule degraders” in J. Medicinal Chemistry (DOI: 10.1021/acs.jmedchem.9b01566). Image: Hi-C maps showing signal in wild-type and Wiz deletion cells (see article for details; click to enlarge). Please see our page...

Megan Justice (Jill Dowen lab) published a paper titled “A WIZ/Cohesin/CTCF complex anchors DNA loops to define gene expression and cell identity” in Cell Reports (DOI: 10.1016/j.celrep.2020.03.067). Image: Hi-C maps showing signal in wild-type and Wiz deletion cells (see article for details; click to enlarge). Please see our page on...

Spencer Nystrom and Matt Niederhuber (Dan McKay lab) published a paper titled “Expression of E93 provides an instructive cue to control dynamic enhancer activity and chromatin accessibility during development” in Development (DOI: 10.1242/dev.181909). Image: Composite image of precocious activity of an enhancer in an imaginal disc and genomics data plotted...

Juan Carvajal Garcia (Dale Ramsden lab and Jeff Sekelsky lab) published an article titled “Mechanistic basis for microhomology identification and genome scarring by polymerase theta” in Proceedings of the National Academy of Sciences (DOI: 10.1073/pnas.1921791117).聽 Image: Model for generation of templated insertions durng theta-mediated repair; see article for details. Please...

The Curriculum in Genetics and Molecular Biology is concerned about the well-being of our students and faculty during this time. We have compiled a list of mental health resources for you to use during this time. This list may be updated from time to time. If you should have any...

All Spring 2020 黑料网 Genetics and Molecular Biology Curriculum courses will be held online effective Monday, March 23, 2020. Contact your course instructor or teaching assistant immediately if you do not have access or have questions. Contact Curriculum Director Jeff Sekelsky or Student Services Manager John Cornett if you should...

Kia Perez-Vale (Mark Peifer lab) was selected to participate in the Yale University Ciencia Initiative. Throughout 2020, Kia will participate in a program designed 鈥渢o expand access to scientific knowledge, experiences, and careers among communities or populations traditionally underrepresented in, or underserved by, the scientific enterprise.鈥�