Monday – FUSION: Leo Bondel, Katie Holmes, & Jake Roetcisoender
Monday – FUSION: Leo Bondel, Katie Holmes, & Jake Roetcisoender
Leo Bondel (Zylka lab) Our goal is to identify guide RNAs targeting the UBE3A-ATS in human neurons, which allow for installation of a Poly(A) signal with cytosine base editors These edits have the potential to restore UBE3A expression, making this an attractive therapeutic strategy for Angelman Syndrome Katie Holmes (Baldwin lab) White matter astrocytes maintain … Read more