BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Department of Cell Biology and Physiology - ECPv6.11.1//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-ORIGINAL-URL:/cellbiophysio X-WR-CALDESC:Events for Department of Cell Biology and Physiology REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20250309T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20251102T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20250421T123000 DTEND;TZID=America/New_York:20250421T133000 DTSTAMP:20250504T185001 CREATED:20250106T193034Z LAST-MODIFIED:20250415T183138Z UID:10000438-1745238600-1745242200@www.med.unc.edu SUMMARY:Monday - FUSION: Jack Bennett\, Lauren Griffith\, & Shenice Harrison DESCRIPTION:Jack Bennett (Cook lab) \n\n\n\nIntracellular pH can be manipulated by inhibiting ion transporters\, and these changes can be measured by flow cytometry\npH manipulations may alter cell cycle progression\, arresting cells in the G1 phase of the cell cycle\n\n\n\n  \n\n\n  \n\n\n \n\n\nLauren Griffith (Williams lab) \n\n\n\nExplore how integrin-β1 and its adaptor protein Talin loss-of function affects oriented cell divisions and telophase correction in fixed tissue and live imaging\nExplore how integrin-β1 and its adaptor protein Talin loss-of function impacts basal cell delamination\n\n\n\n  \n\n\n  \n\n\n \n\n\nShenice Harrison (Edwards lab) \n\n\n\nImpaired myristoylation disrupts sarcomere organization and reduces sarcomere length in embryonic cardiomyocytes\nOptimizing a metabolic labeling strategy to identify the myristoylated cardiac proteins required for proper sarcomere assembly\n\n\n\n  URL:/cellbiophysio/event/monday-fusion-katie-holmes-lauren-griffith-shenice-harrison/ LOCATION:G202 MBRB\, 111 Mason Farm Rd\, Chapel Hill CATEGORIES:FUSION Seminar Series END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20250428T123000 DTEND;TZID=America/New_York:20250428T133000 DTSTAMP:20250504T185001 CREATED:20250106T210736Z LAST-MODIFIED:20250424T133653Z UID:10000439-1745843400-1745847000@www.med.unc.edu SUMMARY:Monday – FUSION: Michelle LaBella & Mady Chlebowski DESCRIPTION:Michelle LaBella (Yeh lab) \n\n\n\nTNIK is required to restrain tumor invasion in PDAC\n\nClear difference in mechanism when compared to colorectal/lung cancer\n\n\nTNIK is a newly identified regulator of PLAT\, tPA expression and ECM modulation through fibrin degradation\nNew mechanism for PDAC invasion and metastasis\, may be what restrains classical tumors\n\n\n\n  \n\n\n  \n\n\n \n\n\nMady Chlebowski (Shiau & Chen labs) \n\n\n\nDistinct neuroimmune and other cell-cell interactions may serve as early signatures of neurodegeneration prior to overt morphological cell death\nThis holds promise for early detection or intervention of neurodegenerative diseases\n\n\n\n  URL:/cellbiophysio/event/monday-fusion-michelle-labella-mady-chlebowski/ LOCATION:G202 MBRB\, 111 Mason Farm Rd\, Chapel Hill CATEGORIES:FUSION Seminar Series END:VEVENT END:VCALENDAR