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Event Category: FUSION Seminar Series

FUSION Seminar Series

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Event Series FUSION Seminar Series

Monday – FUSION: Henry Uchenna, Meghan Anderman, & Ashlyn Laidman

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Henry Uchenna (Maddox lab) Capping Protein depletion accelerates furrowing and cytokinesis, likely due to increased F-actin in the contractile ring It also disrupts spindle dynamics, potentially through effects on the dynein-dynactin complex     Meghan Anderman (McCauley lab) Using human intestinal organoids to model gastrointestinal (GI) pathophysiology in cystic fibrosis Assessing the general role of … Read more

Event Series FUSION Seminar Series

Monday – FUSION: Leo Bondel, Katie Holmes, & Jake Roetcisoender

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Leo Bondel (Zylka lab) Our goal is to identify guide RNAs targeting the UBE3A-ATS in human neurons, which allow for installation of a Poly(A) signal with cytosine base editors These edits have the potential to restore UBE3A expression, making this an attractive therapeutic strategy for Angelman Syndrome     Katie Holmes (Baldwin lab) White matter astrocytes maintain … Read more

Event Series FUSION Seminar Series

Monday – FUSION: Jack Bennett, Lauren Griffith, & Shenice Harrison

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Jack Bennett (Cook lab) Intracellular pH can be manipulated by inhibiting ion transporters, and these changes can be measured by flow cytometry pH manipulations may alter cell cycle progression, arresting cells in the G1 phase of the cell cycle     Lauren Griffith (Williams lab) Explore how integrin-β1 and its adaptor protein Talin loss-of function … Read more

Event Series FUSION Seminar Series

Monday – FUSION: Michelle LaBella & Mady Chlebowski

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Michelle LaBella (Yeh lab) TNIK is required to restrain tumor invasion in PDAC Clear difference in mechanism when compared to colorectal/lung cancer TNIK is a newly identified regulator of PLAT, tPA expression and ECM modulation through fibrin degradation New mechanism for PDAC invasion and metastasis, may be what restrains classical tumors     Mady Chlebowski … Read more

Monday: FUSION – Anna Beeson & Vickie Williams

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Anna Beeson (Caron lab) Adrenomedullin robustly increases both mouse fertility and pinopode formation Alternative model systems are allowing us to interrogate pinopode formation in novel ways     Vickie Williams (Cohen lab) Dimerization fluorescent proteins are a useful tool that can show increased ER-LD contacts under conditions of lipid droplet biogenesis Dimerization-dependent fluorescent proteins can … Read more