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One area of interest is to investigate how the coagulation cascade contributes to the pathophysiology of neuroinflammation using mouse models of stroke and multiple sclerosis. We also study mechanisms of coagulation activation and clot formation in mouse models of sickle cell disease, and our goal is to identify the best...

Research Interests To date, my research interests have focused primarily on the investigation of the coagulation system in inflammatory disorders with a thrombotic phenotype. There is known to be a close interplay between inflammation and coagulation, however, not all inflammation predisposes to thrombosis. My work aims to help better understand...

As part of the Blood Research Center, we use our background in protein chemistry and enzyme kinetics to collaborate on studies looking at the molecular mechanisms that underlie both healthy hemostasis and the dysregulation of hemostasis seen in bleeding and thrombosis. Research Interest Our interest is in the cellular interactions,...

Dr. Moll is a clinician, clinical researcher, and educator, with a particular focus on thrombosis and anticoagulation. His research interests include clinical trials on venous thromboembolism and better use of anticoagulants, antiphospholipid antibody syndrome, and postthrombotic syndrome. A major interest of Dr. Moll is the clinical-medical education of patients, health...

Research Interests The Mackman lab studies the role of tissue factor (TF), coagulation proteases, protease activated receptors (PARs) and extracellular vesicles (EVs) in mouse models of hemostasis, thrombosis, endotoxemia, ischemia-reperfusion injury, cancer, obesity, atherosclerosis and viral infection. My lab has generated and obtained several unique mouse lines that have altered...

Specialty Areas Sickle Cell Disease and erythropoiesis We are interested in the physical properties of red cells, especially from people with sickle cell disease, under ambient and hypoxic conditions. We are using microfluidic devices in collaboration with colleagues at 黑料网 and at CWRU to study red cells and to associate...

Specialty Areas Bleeding and clotting disorders, and Hereditary Hemorrhagic Telangiectasia. My clinical interest is in classical hematology, particularly in bleeding and clotting disorders. I have a special interest in hereditary hemorrhagic telangiectasia (HHT), an inherited rare bleeding disorder. I am Director of the 黑料网 HHT Center of Excellence, a program...