{"id":2575,"date":"2014-10-30T17:57:54","date_gmt":"2014-10-30T21:57:54","guid":{"rendered":"https:\/\/www.med.unc.edu\/toxicology\/drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver\/"},"modified":"2018-06-19T14:14:36","modified_gmt":"2018-06-19T18:14:36","slug":"drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/toxicology\/drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver\/","title":{"rendered":"Drs Watkins and Brouwer developed, DILIsym, a computer program designed to predict how drugs will affect the liver."},"content":{"rendered":"

 <\/p>\n

\n
\"image2\"
<\/figcaption><\/figure>\n<\/div>\n
\n

DILIsym, a computer model developed by the Hamner Institutes for Health Sciences (Dr. Watkins) has been used by researchers at ºÚÁÏÍø to solve a nearly 20 year old mystery about a new drug designed to treat type 2 diabetes \u2013Troglizatone-. After its inception in 1997 it had killed 63 patients by mysteriously inducing liver failure.<\/b><\/p>\n

The research team at the ºÚÁÏÍø Eshelman School of Pharmacy was able to predict outcomes that were actually seen in patients with a model description of the mechanisms that may have caused the liver damage. Dr. Brouwer, senior author of the paper, is very excited how this will change the way of thinking and predicting dangers through drug-induced liver injuries. <\/b><\/p>\n

See full article http:\/\/unc.edu\/spotlight\/a-mystery-solved\/<\/a><\/b><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

  DILIsym, a computer model developed by the Hamner Institutes for Health Sciences (Dr. Watkins) has been used by researchers at ºÚÁÏÍø to solve a nearly 20 year old mystery about a new drug designed to treat type 2 diabetes \u2013Troglizatone-. After its inception in 1997 it had killed 63 patients by mysteriously inducing liver … Read more<\/a><\/p>\n","protected":false},"author":672,"featured_media":2576,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-2575","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/toxicology\/wp-content\/uploads\/sites\/738\/2018\/06\/drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver-image2.jpeg","featured_image_medium":"https:\/\/www.med.unc.edu\/toxicology\/wp-content\/uploads\/sites\/738\/2018\/06\/drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver-image2-300x300.jpeg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/toxicology\/wp-content\/uploads\/sites\/738\/2018\/06\/drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver-image2.jpeg","featured_image_large":"https:\/\/www.med.unc.edu\/toxicology\/wp-content\/uploads\/sites\/738\/2018\/06\/drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver-image2.jpeg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/toxicology\/wp-content\/uploads\/sites\/738\/2018\/06\/drs-watkins-and-brouwer-developed-dilisym-a-computer-program-designed-to-predict-how-drugs-will-affect-the-liver-image2-150x150.jpeg","featured_image_alt":"","category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/toxicology\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/posts\/2575","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/users\/672"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/comments?post=2575"}],"version-history":[{"count":3,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/posts\/2575\/revisions"}],"predecessor-version":[{"id":3206,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/posts\/2575\/revisions\/3206"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/media\/2576"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/media?parent=2575"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/categories?post=2575"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/tags?post=2575"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}