{"id":3839,"date":"2018-07-09T18:25:00","date_gmt":"2018-07-09T22:25:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/tarc\/unc-thurston-arthritis-research-center2019s-john-collins-phd-receives-irene-diamond-fund-afar-postdoctoral-transition-award-in-aging\/"},"modified":"2018-08-22T12:35:43","modified_gmt":"2018-08-22T16:35:43","slug":"unc-thurston-arthritis-research-center2019s-john-collins-phd-receives-irene-diamond-fund-afar-postdoctoral-transition-award-in-aging","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/tarc\/unc-thurston-arthritis-research-center2019s-john-collins-phd-receives-irene-diamond-fund-afar-postdoctoral-transition-award-in-aging\/","title":{"rendered":"ºÚÁÏÍø Thurston Arthritis Research Center\u2019s John Collins, PhD, Receives Irene Diamond Fund\/AFAR Postdoctoral Transition Award in Aging"},"content":{"rendered":"
\n

Dr. Collins, a post-doctoral fellow working in Dr. Richard Loeser\u2019s lab, was selected to receive the $120,000, two-year grant following a rigorous scientific competition held by the American Federation for Aging Research (AFAR). His research currently focuses on determining how age-related increases in oxidative stress levels contribute to disordered cell signaling in joint tissues to promote the development and progression of osteoarthritis (OA).<\/p>\n

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Dr. Collins\u2019 research aims to determine how age-related oxidative stress modifies the activity of a protein called sirtuin 6, which has been shown to increase the lifespan of model organisms.<\/p>\n

Establishing the importance of sirtuin 6 activity in joint tissues and defining how the cell signaling capabilities of sirtuin 6 are altered as we age will provide us with a better understanding of how aging contributes to the development of OA. This could lead to new targeted therapies that slow or stop OA progression.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Dr. Collins, a post-doctoral fellow working in Dr. Richard Loeser\u2019s lab, was selected to receive the $120,000, two-year grant following a rigorous scientific competition held by the American Federation for Aging Research (AFAR). His research currently focuses on determining how age-related increases in oxidative stress levels contribute to disordered cell signaling in joint tissues to promote the development and progression of osteoarthritis (OA).<\/p>\n","protected":false},"author":58060,"featured_media":3840,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-3839","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nºÚÁÏÍø Thurston Arthritis Research Center\u2019s John Collins, PhD, Receives Irene Diamond Fund\/AFAR Postdoctoral Transition Award in Aging | Thurston Arthritis Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/tarc\/unc-thurston-arthritis-research-center2019s-john-collins-phd-receives-irene-diamond-fund-afar-postdoctoral-transition-award-in-aging\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ºÚÁÏÍø Thurston Arthritis Research Center\u2019s John Collins, PhD, Receives Irene Diamond Fund\/AFAR Postdoctoral Transition Award in Aging | Thurston Arthritis Research Center\" \/>\n<meta property=\"og:description\" content=\"Dr. Collins, a post-doctoral fellow working in Dr. Richard Loeser\u2019s lab, was selected to receive the $120,000, two-year grant following a rigorous scientific competition held by the American Federation for Aging Research (AFAR). 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