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The Carolina Stress Initiative is a collaborative effort between clinical and basic scientists to improve our understanding of trauma and stress-related disorders.

Stress-related psychiatric disorders, including major depression, post-traumatic stress, and anxiety disorders, are the most common mental illnesses in the United States. With the recent Covid19 pandemic, both the Center for Disease Control and the National Institute of Health predict that the number of people suffering from trauma and stress-related disorders will rise dramatically and to potentially catastrophic proportions. To address this call to action, the 黑料网 Department of Psychiatry is launching the Carolina Stress Initiative (CSI), with the primary mission to conduct key translational research to improve understanding and treatment of trauma and stress-related disorders. This mission is pursued by bringing together basic and clinical researchers with complementary expertise on neuropsychiatric epigenetics and the use of animal models in neuroscience. The ultimate goal is to develop novel therapeutic strategies for stress-related disorders.

Stress-Related Disorders

Traumatic Event.聽A traumatic event is a shocking, scary, or life-threatening experience that can affect someone emotionally and physically. Experiences like pandemics, natural disasters, acts of violence, as well as car crashes and other accidents can all be traumatic. We are therefore investigating the factors that may help people cope with these events or increase their risk for physical or mental health problems following a traumatic event. For more information please visit:聽

Post-Traumatic Stress.聽Post-traumatic stress disorder (PTSD) develops in some people who have experienced a shocking, scary, or life-threatening event. Fear triggers many split-second changes in the body to help defend against danger or to avoid it. This 鈥渇ight-or-flight鈥� response is a typical reaction meant to protect a person from harm. Most people recover from these initial symptoms naturally, but those who continue to experience persistent symptoms may be diagnosed with PTSD. For more information please visit:聽

Major Depression.聽Major depressive disorder (MDD) is one of the most common mental disorders, afflicting one in five women and one in ten men at least once during their lifetime. MDD is a leading cause of disability worldwide, and its symptoms can interfere with daily activities such as job performance, school work, and relationships. While the cause of MDD is in many cases unknown, for many individuals the disorder develops during periods of excessive or chronic exposure to stress. For more information please visit:聽

Anxiety Disorders.聽Occasional anxiety is an expected part of life. You might feel anxious when faced with a problem at work, before taking a test, or before making an important decision. But anxiety disorders involve more than temporary worry or fear. For a person with an anxiety disorder, the anxiety does not go away and can get worse over time. The symptoms can interfere with daily activities such as job performance, school work, and relationships. There are several types of anxiety disorders, including generalized anxiety disorder, panic disorder, and various phobia-related disorders. For more information please visit:聽