Rachel Babcock
Postdoctoral Researcher
Areas of Interest
Use of DVL chromatin immunoprecipitation (ChIP) assay to reveal novel DVL1 binding at immune genes in triple negative breast caner (TNBC) cell lines
About
Research Aims: Study triple negative breast cancer (TNBC) cell lines to:
- Identify and assess DVL1-regulated immune genes
- Establish DVL1 loss and gain of function systems to study DVL1-regulated genes
- Identify nuclear DVL1 transcription factor (TF) partners
- Molecular assays to assess nuclear DVL1:TF interactions
- Determine DVL1 roles in TNBC anti-tumore immunity
- Establish DVL1 sufficient and defficient TNBC tumor models to assess the anti-tumor immune response
DVL chromatin immunoprecipitation (ChIP) assay revealed novel DVL1 binding at immune genes in triple negative breast caner (TNBC) cell lines.
