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Published in Nature, research from the lab of Bryan L. Roth, MD, PhD, Distinguished Professor of Pharmacology, revealed the first-ever crystal structure of the dopamine 2 receptor bound to an antipsychotic drug – a much-needed discovery in the quest to create effective drugs with fewer side effects to treat bipolar...

The lab of Jean Cook, PhD, joint professor in the department of pharmacology, found how a chain of proteins called an MCM complex could enable the fast cell-division that makes some forms of cancer so dangerous.

In a paper published in Cell, research led by Bryan Roth, MD, PhD, and Roth lab members, Tao Ch, PhD and Daniel Wacker, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads...

Carolina has surpassed, for the first time, $1 billion in annual research expenditures, according to the nation’s annual Higher Educa- tion Research and Development survey. This news continues Carolina’s decade-long rise as one of the world’s top universities for spon- sored research. The latest survey covers fiscal year 2016 and...

Led by Timothy Elston, PhD, and Chuck Perou, PhD, the university-wide program aims to advance personalized medicine for patients.

Wesley Legant, PhD, Assistant Professor in Pharmacology, is highlighted in a Nature article on a do-it-yourself approach to microscopy that lead to the development of light sheet microscopy.

The center, established 20 years ago and led by Fulton Crews, PhD, Distinguished Professor in Pharmacology, will receive more than $8.7 million over five years to continue research on the effects of alcohol on the brain. Other pharmacology faculty who are PIs on the the grant are Clyde Hodge, PhD,...

Research led by ºÚÁÏÍø’s Jonathan Schisler, PhD, Assistant Professor of Pharmacology, showed much lower levels of the protein CXCL5 in older people with clogged arteries.

In a new study published in Cell Stem Cell, ºÚÁÏÍø neuroscientist Juan Song and colleagues discovered a long-distance brain circuit that controls the production of new neurons in the hippocampus.