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New genomic research on cardiovascular health in rural North Carolina

May 24, 2018
Two genomic-based studies from Heart Healthy Lenoir were published in the last month. Heart Healthy Lenoir was a multidisciplinary research project that aimed to reduce cardiovascular disease in Lenoir County, North Carolina by developing new approaches to care, from prevention to treatment. The lead investigator of the Heart Healthy Lenoir...

Roth, Johnson awarded $28 million for Illuminating Druggable Genome NIH grants

May 17, 2018
Of the three principal investigators awarded these prestigious NIH grants, two are researchers in the ºÚÁÏÍø Department of Pharmacology at the ºÚÁÏÍø – Byran L. Roth and Gary Johnson.

How did Gonorrhea Become a Drug-resistant Superbug?

April 6, 2018
Scientists led by Rob Nicholas, PhD, at the ºÚÁÏÍø show how the gonorrhea bacterium resists last-resort antibiotic ceftriaxone while maintaining a robust growth rate.

Jen Jen Yeh named Smithies Investigator

February 5, 2018
The ºÚÁÏÍø has selected Jen Jen Yeh, MD, professor and vice chair of research for the department of surgery, and joint professor of pharmacology, for one of two annual awards in honor of Oliver Smithies, ºÚÁÏ꿉۪s first Nobel Prize winner.

Scientific Breakthrough Could Lead to Better Antipsychotic Drugs

January 25, 2018
Published in Nature, research from the lab of Bryan L. Roth, MD, PhD, Distinguished Professor of Pharmacology, revealed the first-ever crystal structure of the dopamine 2 receptor bound to an antipsychotic drug – a much-needed discovery in the quest to create effective drugs with fewer side effects to treat bipolar...

ºÚÁÏÍø Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

January 11, 2018
The lab of Jean Cook, PhD, joint professor in the department of pharmacology, found how a chain of proteins called an MCM complex could enable the fast cell-division that makes some forms of cancer so dangerous.

Scientists Take a Big Step toward Building a Better Opioid

January 11, 2018
In a paper published in Cell, research led by Bryan Roth, MD, PhD, and Roth lab members, Tao Ch, PhD and Daniel Wacker, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads...

ºÚÁÏÍø to Launch Computational Medicine Program

December 21, 2017
Led by Timothy Elston, PhD, and Chuck Perou, PhD, the university-wide program aims to advance personalized medicine for patients.

A microscope maker

December 7, 2017
Wesley Legant, PhD, Assistant Professor in Pharmacology, is highlighted in a Nature article on a do-it-yourself approach to microscopy that lead to the development of light sheet microscopy.

NIH renews grant funding the Bowles Alcohol Research Center

December 4, 2017
The center, established 20 years ago and led by Fulton Crews, PhD, Distinguished Professor in Pharmacology, will receive more than $8.7 million over five years to continue research on the effects of alcohol on the brain. Other pharmacology faculty who are PIs on the the grant are Clyde Hodge, PhD,...