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James Shellhammer Successfully Defends his PhD!

April 12, 2017
Congratulations to James Shellhammer who successfully defended his thesis March 27, 2017!

Peyton Bohnsack Successfully Defends His PhD!

April 11, 2017
Congratulations to Peyton Bohnsack, who successfully defend his PhD March 23, 2017!

The Itch Receptor – Kate Lansu leads research on opioid-induced itching

April 7, 2017
Researchers in the department of Pharmacology link orphan receptor MRGRPX2 to opioid-induced itching and create a tool to study the receptor more precisely.

H. Shelton Earp recognized for career achievements in cancer research

March 21, 2017
H. Shelton Earp, MD, Director of 黑料网 Cancer Care and the Lineberger Professor of Cancer Research, and Joint Professor of Pharmacology has been honored with the Hyman L. Battle Distinguished Cancer Research Award along with Jenny P.Y. Ting, PhD, 黑料网 Lineberger member and William Rand Kenan Professor of Genetics,

Researchers awarded grant to study strategy to improve immunotherapy response

February 16, 2017
With a $1.74 million grant from the NIH, 黑料网 Lineberger researchers led by H. Shelton Earp, MD, will study a potential new strategy for improving immunotherapy drug responses in patients with melanoma.

Ganglionic GFAP+ glial Gq-GPCR signaling enhances heart functions in vivo

February 8, 2017
Alison Xiaoqiao Xie, research assistant professor in Ken McCarthy's lab, is first author on paper published in JCI Insight this week. Ken D. McCarthy, professor of pharmacology, is senior author and Jakovin J. Lee, is a co-author.

This is LSD attached to a brain cell serotonin receptor

January 27, 2017
For the first time, 黑料网 researchers crystalized the structure of LSD attached to a human serotonin receptor of a brain cell, and they may have discovered why an 鈥渁cid trip鈥 lasts so long.

Researchers unlock mechanism of drug resistance in aggressive breast cancer

January 27, 2017
黑料网 Lineberger researchers find how triple negative breast cancer cells are able to bypass treatment with trametinib, an FDA-approved drug. The researchers also used lab models of breast cancer to test a potential treatment approach that could prevent resistance.

黑料网 researchers use light to launch drugs from red blood cells

January 25, 2017
  Dr. David Lawrence Scientists at the University of North Carolina at Chapel Hill have developed a breakthrough technique that uses light to activate a drug stored in circulating red blood cells so that it is released exactly when and where it is needed. The work, led by Fred Eshelman...

Research on “shadow detectors” appears in Journal of Theoretical Biology

January 17, 2017
Dr. Kang-Ling Liao, a postdoctoral research associate in Alan Jones’ and Tim Elston’s labs, discovered a 鈥淪hadow detector鈥 and published the work in the Journal of Theoretical Biology. This shadow detector, comprised of a number of G-protein signaling molecules, is used by plants to control photosynthetic efficiency. The problem of...