1.0Department of Pathology and Laboratory Medicine/pathologyDavid Williams/pathology/author/dcwilljr/rich600338<blockquote class="wp-embedded-content" data-secret="HHslLvRVBi"><a href="/pathology/directory/dcwilljr/">David Williams</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="/pathology/directory/dcwilljr/embed/#?secret=HHslLvRVBi" width="600" height="338" title="“David Williams” — Department of Pathology and Laboratory Medicine" data-secret="HHslLvRVBi" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); /* ]]> */ </script> /pathology/wp-content/uploads/sites/646/2018/04/WilliamsDavid2013.jpg188250Research Interests My laboratory uses structural and biophysical techniques to probe protein-protein and protein-DNA interactions critical to the formation of macromolecular complexes. Over the past several years, we have been studying the Nucleosome Remodeling and Deacetylase (NuRD) complex responsible for recognizing methylated DNA and silencing expression of the associated genes. Our focus has been to understand how a key component … Read more