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We study protein structure and dynamics as they relate to protein function and energetics. We are currently using NMR spectroscopy (e.g. spin relaxation), computation, and a variety of other biophysical techniques to gain a deeper understanding of proteins at atomic level resolution.聽 Of specific interest is the general phenomenon of long-range communication within protein structures, such as observed in allostery and conformational change.聽 A. Lee is a member of the Molecular & Cellular Biophysics Training Program.,We study protein structure and dynamics as they relate to protein function and energetics. We are currently using NMR spectroscopy (e.g. spin relaxation), computation, and a variety of other biophysical techniques to gain a deeper understanding of proteins at atomic level resolution.聽 Of specific interest is the general phenomenon of long-range communication within protein structures, such as observed in allostery and conformational change.聽 A. Lee is a member of the Molecular & Cellular Biophysics Training Program.
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CLINICAL/RESEARCH INTERESTS:
Biochemistry, Biophysics, Computational Biology, Structural Biology |