Luther Bartelt is an early investigator who studies intestinal infectious organisms with complex pathogenesis, namely Giardia and Cryptosporidium.\u00a0 He has board certification in clinical Infectious Diseases, expertise in clinical and laboratory Tropical Medicine, and active care of immunocompromised patients. He completed an NIDDK-sponsored post-doctoral fellowship, and he is currently supported by an NIAID-sponsored Career Development Award. Working with Dr. Richard Guerrant during post-doctoral training at the University of Virginia, he developed a novel murine model of giardiasis that recapitulated features of both chronic infections in adults, as well as findings associated with infections in malnourished children. Intestinal bacteria, both resident and pathogenic, were observed to influence the pathogenesis of giardiasis during malnutrition.\u00a0 These findings led to the development of a collaboration with Balfour Sartor and subsequent recruitment to 黑料网.\u00a0 Through the CGIBD pilot feasibility project award, he developed a novel Giardia mono-association model for the purposes of more rigorous and defined examination of the role of key microbe-microbe interactions in the pathogenesis of giardiasis and early life pathogen exposures. \u00a0Key published findings have identified parasite-mediated metabolic perturbations in gut microbial protein degradation pathways and the ability of antibiotics without anti-giardial activity to prevent growth impairment during giardiasis.\u00a0 Preliminary data suggest that Giardia, separate from resident intestinal bacteria does not significantly impair growth during protein malnutrition.<\/p>\n","protected":false},"featured_media":4251,"template":"","meta":{"_acf_changed":false},"affiliation":[203,48,49],"database-category":[292],"expert-year":[287],"class_list":["post-4250","faculty-expert","type-faculty-expert","status-publish","has-post-thumbnail","hentry","affiliation-dom-infdis","affiliation-cgibd","affiliation-medicine","database-category-gut-health-and-diseases","expert-year-287","odd"],"acf":[],"yoast_head":"\n