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Grand Rounds – Tolerogenic Vaccination as a Myelin-Specific Therapy for Autoimmune Demyelinating Disease of the CNS
February 2, 2017 @ 8:00 am - 9:00 am
Tolerogenic Vaccination as a Myelin-Specific Therapy for Autoimmune Demyelinating Disease of the CNS
Mark D. Mannie, PhD
The Brody School of Medicine
East Carolina University
Objectives:
- Describe experimental strategies of tolerogenic vaccination for induction of FOXP3+ regulatory T cells.
- Discuss properties by which cytokines IFN-β and GM-CSF can be used to drive regulatory T cell responses.
- Explain mechanisms of ‘infectious’ tolerance regarding induction of polyclonal tolerance to the CNS.
February 2, 2017, 8 – 9 am
CG222, Sanofi-Aventis Conference Center, NCCH Room #1
Sponsored by the School of Medicine of The University of North Carolina at Chapel Hill.