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TeamLeadership

Yael Shiloh-Malawsky, MD

Clinical Core Leader, Co-founder
ENGI Research Projects

Yael Shiloh-Malawsky, MD, is a board-certified child neurologist and epileptologist. She co-founded the Epilepsy Neurogenetics Initiative (ENGI) and the pediatrics neurogenetics workgroup in response to new clinical needs in this fast-evolving field. Dr. Shiloh-Malawsky teamed with neurologists Dr. Senyene Hunter (a physician-scientist with clinical and research focus in epilepsy genetics) and Dr. Jane Fan (trained in child neurology, genetics, and sleep medicine), metabolic-genetics specialist Dr. Muge Calikoglu, and with genetic counselor Jenna Lea.

Together, these specialists established a multidisciplinary expert team to maximize the benefits of scientific advancement in epilepsy genetics and patient care. The Clinical Core collaboration, led by Dr. Shiloh-Malawsky, focuses on three main objectives:

  1. Improving the process and efficiency of genetic testing in pediatric epilepsy;
  2. Complex case resolution, bi-monthly round table consultations of challenging clinical cases by a multidisciplinary expert panel that reviews, discusses, and recommends to referring physicians the best plan of care;
  3. Standardizing and updating epilepsy genetics evaluations and consults, through a process of continual review and response to new advances and emerging resources in the field.

The ENGI Clinical Core places ºÚÁÏÍø as a leader in epilepsy genetic care. It provides patients across North Carolina access to specialized neurogenetics services, resources, and consultations.


Senyene Hunter, MD, PhD

Research Core Leader, Co-founder
ENGI Research Projects

Senyene Hunter, MD, PhD, a physician-scientist, is co-founder of the Epilepsy Neurogenetics Initiative (ENGI). As the Research Core leader, Dr. Hunter partners with research collaborators and basic scientists to study best practices and guide future implementation of genomic technologies. The Research Core’s basic science collaborations aim to improve the understanding of cellular, molecular, and nervous system functions underlying epilepsy genetics and identify pathogenic gene variants and candidate risk genes.

In addition, the Research Core aims to provide patients with state-of-the-art care by improving patient access to clinical trials and translational research, connecting families to local, regional, and national studies, and linking patients to genetic-specific treatment clinical trials.


Jenna Lea, MS, CGC

Jenna Lea, MS, CGC, is a board-certified, clinical genetic counselor with ºÚÁÏÍø Neurology, Neurogenetics Division. She primarily works in pediatric neurogenetics, as well as Huntington disease, and joined the Epilepsy Neurogenetics Initiative (ENGI) in July 2022. As a clinical genetic counselor, she determines practice guideline-supported test selection from clinical and family history, ensures informed decision-making, and completes results interpretation and in-depth post-test counseling. Her aim is to provide personalized, patient-friendly education and resources on the medical, psychological, and familial implications of genetic testing and genetic epilepsy diagnoses.

 

Meet Our Team

Neurology

Child Neurologists who specialize in genetic epilepsies and neurogenetic disorders:

Zheng (Jane) Fan, MD

Co-division Chief of Precision Medicine and Neurogenetics
Medical Director of sleep Laboratory
Professor of Neurology

 

Diana Cejas, MD, MPH

Associate Professor, Child Neurology
Dual Appointment with the Carolina Institute of Developmental Disabilities

 

Qian-Zhou (Jojo) Yang, MD

Assistant Professor, Child Neurology and Epilepsy
Director of Pediatric Epilepsy Monitoring Unit


Neuroradiologist who specialized in diagnostic imaging of the brain, spine, head, and neck, particularly in pediatric neuroradiology:

Sheng-Che (Alex) Hung, MD, PhD

Associate Professor


Genetics

Pediatric Geneticists with expertise in metabolic and neurogenetic disorders:

Muge Calikoglu, MD, MPH

Associate Professor, Pediatric Genetics and Metabolism, Department of Pediatrics
Assistant Director, Medical Genetics Residency Program

Elizabeth Jalazo, MD

Assistant Professor, Pediatric Genetics and Metabolism

Clara Hildebrandt, MD

Assistant Professor, Pediatrics Genetics and Metabolism


Genetic counselors with experience and specialization in pediatric neurogenetic disorders:

Kimberly Foss, MS, CGC

Clinical Associate Professor, Genetic Counselor

Kristin Clinard, MS, CGC

Clinical Assistant Professor, Pediatric Genetics and Metabolism

Hailey Segall, MS, CGC

Assistant Professor of Neurology, Neurogenetics


Patient and Family Support

Social Worker

Dietary Treatment


Referral and Care Coordinators

 

Additional Support and Resources

Neuropsychology

Hannah Allen, PhD

Assistant Professor, Physical Medicine and Rehabilitation

Expertise in the cognitive, behavioral, and social-emotional outcomes of epilepsy, neurogenetic conditions, and intellectual and developmental disabilities (IDD)