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Research Interest: Our laboratory is specifically interested in the regulation of endothelial cell commitment, differentiation and cell cycle progression, and defining signaling pathways that modulate these processes. We also aim to understand how some endothelial cells acquire specialized functions, such as the generation and/or maintenance of multi-lineage stem/progenitor cells.  

Jonathan Brown, MD, is a cardiologist and basic scientist studying transcriptional mechanisms relevant to the pathogenesis of obesity, diabetes mellitus, and atherosclerosis. A central premise of his research involves a deeper understanding of the gene regulatory networks controlling disease pathogenesis to identify novel therapeutic targets to treat these prevalent and often fatal conditions. More specifically, … Read more