{"id":57831,"date":"2021-12-31T22:34:36","date_gmt":"2022-01-01T03:34:36","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=57831"},"modified":"2023-06-06T18:17:51","modified_gmt":"2023-06-06T22:17:51","slug":"cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/","title":{"rendered":"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI"},"content":{"rendered":"
\"matt-cavender-cangrelor-reduces-ischemic-events\"
Matthew Cavender, MD, MPH<\/figcaption><\/figure>\n

Treatment with the IV P2Y12 inhibitor cangrelor reduced the number of early ischemic events after PCI, primarily MI and stent thrombosis, compared with oral clopidogrel, according to the results of the CHAMPION PHOENIX trial.<\/p>\n

\u201cPatients undergoing PCI are at risk of activation of the clotting process, formation of intravascular thrombus and subsequent myocardial infarction,\u201d said\u00a0Matthew A. Cavender<\/a>, MD, MPH,\u00a0interventional cardiologist and assistant professor of medicine in the division of cardiology, in a new article about the study. \u201cAs such, adjunctive pharmacology used at the time of PCI is designed to prevent thrombus formation by inhibiting both platelet activation<\/a> and thrombin formation.\u201d<\/p>\n

Read the article published in Cardiology Today.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Treatment with the IV P2Y12 inhibitor cangrelor reduced the number of early ischemic events after PCI, primarily MI and stent thrombosis, compared with oral clopidogrel, according to the results of the CHAMPION PHOENIX trial. \u201cPatients undergoing PCI are at risk of activation of the clotting process, formation of intravascular thrombus and subsequent myocardial infarction,\u201d said\u00a0Matthew … Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":40194,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[86,2],"tags":[631],"class_list":["post-57831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cardiology","category-news","tag-631","odd"],"acf":[],"yoast_head":"\nCavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Treatment with the IV P2Y12 inhibitor cangrelor reduced the number of early ischemic events after PCI, primarily MI and stent thrombosis, compared with oral clopidogrel, according to the results of the CHAMPION PHOENIX trial. \u201cPatients undergoing PCI are at risk of activation of the clotting process, formation of intravascular thrombus and subsequent myocardial infarction,\u201d said\u00a0Matthew … Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ºÚÁÏÍøDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2022-01-01T03:34:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T22:17:51+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"549\" \/>\n\t<meta property=\"og:image:height\" content=\"768\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Kim Morris\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@uncdeptmedicine\" \/>\n<meta name=\"twitter:site\" content=\"@uncdeptmedicine\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Kim Morris\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/\",\"url\":\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/\",\"name\":\"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI | Department of Medicine\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg\",\"datePublished\":\"2022-01-01T03:34:36+00:00\",\"dateModified\":\"2023-06-06T22:17:51+00:00\",\"author\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/#\/schema\/person\/9a358414a53d5237f9ba3f8daa55c529\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg\",\"width\":549,\"height\":768,\"caption\":\"Matthew Cavender, MD, MPH\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/medicine\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/medicine\/\",\"name\":\"Department of Medicine\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/medicine\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/#\/schema\/person\/9a358414a53d5237f9ba3f8daa55c529\",\"name\":\"Kim Morris\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/024aa9afd2b3b88ae4d3857b86388e7f?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/024aa9afd2b3b88ae4d3857b86388e7f?s=96&d=mm&r=g\",\"caption\":\"Kim Morris\"},\"description\":\"Medicine - Dept of\",\"url\":\"https:\/\/www.med.unc.edu\/medicine\/news\/author\/kcmorris\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI | Department of Medicine","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/","og_locale":"en_US","og_type":"article","og_title":"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI | Department of Medicine","og_description":"Treatment with the IV P2Y12 inhibitor cangrelor reduced the number of early ischemic events after PCI, primarily MI and stent thrombosis, compared with oral clopidogrel, according to the results of the CHAMPION PHOENIX trial. \u201cPatients undergoing PCI are at risk of activation of the clotting process, formation of intravascular thrombus and subsequent myocardial infarction,\u201d said\u00a0Matthew … Read more","og_url":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/","og_site_name":"Department of Medicine","article_publisher":"https:\/\/www.facebook.com\/ºÚÁÏÍøDeptMedicine","article_published_time":"2022-01-01T03:34:36+00:00","article_modified_time":"2023-06-06T22:17:51+00:00","og_image":[{"width":549,"height":768,"url":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg","type":"image\/jpeg"}],"author":"Kim Morris","twitter_card":"summary_large_image","twitter_creator":"@uncdeptmedicine","twitter_site":"@uncdeptmedicine","twitter_misc":{"Written by":"Kim Morris","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/","url":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/","name":"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI | Department of Medicine","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/medicine\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg","datePublished":"2022-01-01T03:34:36+00:00","dateModified":"2023-06-06T22:17:51+00:00","author":{"@id":"https:\/\/www.med.unc.edu\/medicine\/#\/schema\/person\/9a358414a53d5237f9ba3f8daa55c529"},"breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#primaryimage","url":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg","contentUrl":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg","width":549,"height":768,"caption":"Matthew Cavender, MD, MPH"},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/medicine\/news\/cavender-discusses-study-showing-cangrelor-reduces-ischemic-events-versus-clopidogrel-early-after-pci\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/medicine\/"},{"@type":"ListItem","position":2,"name":"Cavender Discusses Study Showing Cangrelor Reduces Ischemic Events Versus Clopidogrel Early After PCI"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/medicine\/#website","url":"https:\/\/www.med.unc.edu\/medicine\/","name":"Department of Medicine","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/medicine\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.med.unc.edu\/medicine\/#\/schema\/person\/9a358414a53d5237f9ba3f8daa55c529","name":"Kim Morris","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/medicine\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/024aa9afd2b3b88ae4d3857b86388e7f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/024aa9afd2b3b88ae4d3857b86388e7f?s=96&d=mm&r=g","caption":"Kim Morris"},"description":"Medicine - Dept of","url":"https:\/\/www.med.unc.edu\/medicine\/news\/author\/kcmorris\/"}]}},"featured_image":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg","featured_image_medium":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender-214x300.jpeg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg","featured_image_large":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender.jpeg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/02\/matt-cavender-150x150.jpeg","featured_image_alt":"matt-cavender-cangrelor-reduces-ischemic-events","category_details":[{"name":"Cardiology","link":"https:\/\/www.med.unc.edu\/medicine\/news\/category\/cardiology\/"},{"name":"News","link":"https:\/\/www.med.unc.edu\/medicine\/news\/category\/news\/"}],"tag_details":[{"name":"2022","link":"https:\/\/www.med.unc.edu\/medicine\/news\/tag\/2022\/"}],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/posts\/57831","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/users\/69419"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/comments?post=57831"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/posts\/57831\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/media\/40194"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/media?parent=57831"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/categories?post=57831"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/medicine\/wp-json\/wp\/v2\/tags?post=57831"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}