{"id":2589,"date":"2015-11-24T23:09:00","date_gmt":"2015-11-25T04:09:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/people\/knowles\/"},"modified":"2023-10-13T12:15:04","modified_gmt":"2023-10-13T16:15:04","slug":"knowles","status":"publish","type":"ud_entry","link":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/people\/knowles\/","title":{"rendered":"Michael Knowles, MD"},"content":{"rendered":"<p><!-- title_affiliation --><\/p>\n<div>\n<h4><strong style=\"font-size: 14px\">Research Focus: <\/strong><span style=\"font-size: 14px\">Dr. Michael R. Knowles is a Professor of Pulmonary and Critical Care Medicine at ºÚÁÏÍø. He has over 3 decades of clinical research experience that spans across the disciplines of biology, physiology, genetics and clinical trials in both the academic and private sectors. He is currently the head of two large multicenter studies: 1) Genetic Modifiers of Disease phenotype (severity) in cystic fibrosis lung and liver disease, which includes an International Consortium doing whole genome and differential gene expression studies; and 2) a Consortium with 8 sites in North America to study rare genetic disorders of mucociliary clearance, and non-CF\/non-PCD (idiopathic) bronchiectasis.<\/span><\/h4>\n<div>\n<div class=\"row\">\n<div class=\"directory-post-content\">\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div>\n<div class=\"mceContentBody documentContent template- portaltype-uncsom-directory-person site-cfpulmcenter section-people subsection-michael-r-knowles-md icons-on userrole-authenticated userrole-site administrator userrole-owner userrole-editor userrole-reader userrole-contributor userrole-reviewer\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"featured_media":2591,"menu_order":24,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"ud_division":[55,95,80],"class_list":["post-2589","ud_entry","type-ud_entry","status-publish","format-standard","has-post-thumbnail","hentry","ud_division-faculty","ud_division-our-faculty-syndication","ud_division-center-for-bronchiectasis","odd"],"acf":[],"ud_entry_custom_fields":{"ud_last_name":"Knowles","ud_first_name":"Michael","ud_gallery_summary":"","ud_telephone":[{"ud_location":"Office","ud_number":"9199666780"}],"ud_email":"","ud_positions":[{"ud_title":"Professor of Medicine"}],"ud_options":[],"ud_sort_order":""},"featured_image":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2022\/07\/Knowles-2nd-pose-Feb-2016-2.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2022\/07\/Knowles-2nd-pose-Feb-2016-2-214x300.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2022\/07\/Knowles-2nd-pose-Feb-2016-2-768x1075.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2022\/07\/Knowles-2nd-pose-Feb-2016-2-731x1024.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2022\/07\/Knowles-2nd-pose-Feb-2016-2-150x150.jpg","yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Michael Knowles, MD - Division of Pulmonary Diseases and Critical Care Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/people\/knowles\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Michael Knowles, MD - Division of Pulmonary Diseases and Critical Care Medicine\" \/>\n<meta property=\"og:description\" content=\"Michael E. 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