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Which Type of Immunity Is Best Against Variants? More Symptoms, More Spread and Other COVID-19 News

September 4, 2021
An article in Infection Disease Special Edition reviews recent studies about COVID-19 transmission, including one聽led by聽Jessica Lin, MD, that showed COVID-19 spreads quickly through a household.聽The observational study, conducted between April and October 2020, followed 100 patients who tested positive for COVID-19 around the Raleigh, N.C., area and included a...

Cooper Promises Expanded Access to COVID Antibody Treatment

September 4, 2021
On the same day North Carolina hospitals reported a record number of COVID-19 patients in intensive care units across the state, Gov. Roy Cooper signaled he will take action expanding access to a potentially lifesaving treatment designed to keep people out of the hospital in the first place. 鈥淲e鈥檝e been...

How Safe Are Outdoor Events? Is a Lockdown Coming?

September 3, 2021
Eighteen months into the pandemic and there are still a lot of questions out there about everything related to COVID-19. CBS 17 took those questions to health experts to get answers using facts not fear. David Weber, MD, MPH, professor of medicine in the division of infectious diseases, contributed to...

Experimental Monoclonal Antibody Combo Shows Significant Efficacy Against COVID-19

September 3, 2021
As part of the NIH-sponsored ACTIV-2 clinical trial for COVID-19 outpatients, preliminary data revealed that a new combination monoclonal antibody treatment reduced hospitalizations and death by 78 percent in high-risk patients. ACTIV-2 vice chair David Wohl, MD, leads monoclonal treatment for 黑料网 Health. Read more from the 黑料网 Health and...

Hobbs and Duncan Win $3.9M NIAID Grant to Study a Meningitis Vaccine鈥檚 Effect on Gonorrhea

September 2, 2021
The NIH鈥檚 National Institute of Allergy and Infectious Diseases has awarded Marcia Hobbs, PhD, and Alex Duncan, MD, PhD, a five-year, $3.9 million grant to study how a vaccine recently developed to prevent life-threatening infections caused by group B Neisseria meningitidis, the MenB vaccine, may also protect people from infection...

Transmission Rate of COVID-19 Within Households Can Be Over 30%, More than 50% from Minority Communities

September 2, 2021
With potent virulence and transmissibility, the SARS-CoV-2 virus is one of the deadliest pathogens to be encountered in recorded history. Scientists have reiterated that other than hygienic measures, distance between individuals is the best defense against its spread. However, the latter is difficult within a household and presents challenges in...

Mask Guidance Evolves Indoors and Outdoors as Delta Variant Keeps Spreading

September 2, 2021
Precautions are changing as the highly contagious Delta variant spreads. Now, experts say even in outdoor settings, a mask is still strongly encouraged in many instances. The Director of Infection Prevention at 黑料网 Medical Center, Emily Sickbert-Bennett, PhD, MS, understands the frustration. She says we now know much more about...

NC Now Using More COVID-19 Treatment in 1 Week Than Previously in 1 Month

September 2, 2021
Monoclonal antibodies are infusion-based therapies used to treat COVID-19 infections. They are being used under Emergency Use Authorization by the FDA. 鈥淲e designed antibodies that we can infuse into someone鈥檚 blood, and instantaneously there are now antibodies,鈥 said David Wohl, MD, professor of medicine in the division of infectious diseases,...

Loehr, Cavanaugh Lead VCAG Project to Enhance Care For Patients Who Have Heart Failure With Reduced Ejection Fraction

September 1, 2021
Heart failure is a common cause of hospitalization and re-hospitalization, particularly in individuals over the age of 65. And approximately half the people who are hospitalized with heart failure (HF) have reduced ejection fraction (HRrEF). A normal ejection fraction is more than 55%, while heart failure with reduced ejection fraction...

Nash 黑料网 Health Receives AHA鈥檚 2021 Mission: Lifeline庐 NSTEMI Gold Quality Achievement Award and STEMI Gold Receiving Center Hospital Achievement Award

August 31, 2021
Nash 黑料网 Health in Rocky Mount, NC, has received the American Heart Association鈥檚 Mission: Lifeline庐 NSTEMI Gold Quality Achievement Award and STEMI Gold Receiving Center Achievement Award for implementing specific quality improvement measures for the treatment of patients who suffer heart attacks.聽Each year more than 250,000 people experience STEMI,聽the deadliest...

Chemotherapy Plus Immunotherapy Before Surgery is Beneficial For Invasive Bladder Cancer Outcomes

August 30, 2021
A new study is the first to report the beneficial use of chemotherapy plus immunotherapy before surgical removal of the bladder in muscle-invasive bladder cancer (MIBC). Researchers at the 黑料网 Lineberger Comprehensive Cancer Center led the study, reporting that the regimen reduced the invasiveness of the cancer in 56 percent...

Novel CRISPR-Based Malaria Diagnostic Capable of Plasmodium Detection, Species Differentiation, and Drug-Resistance Genotyping

August 30, 2021
CRISPR-based diagnostics are a new class of highly sensitive and specific assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific High-Sensitivity Enzymatic Reporter UnLOCKing, is one such CRISPR-based diagnostic that combines recombinase polymerase pre-amplification, CRISPR-RNA base-pairing, and LwCas13a activity for nucleic acid detection. Researchers from the division of...