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Catherine Fahey (Kim Rathmell and Ian Davis labs) and Julia DiFiore (Brian Strahl lab) published an article titled “Structure/function analysis of recurrent mutations in SETD2 reveals a critical and conserved role for a SET domain residue in maintaining protein stability and H3K36 trimethylation” in Journal of Biology Chemistry (online ahead...

Taylor Penke (Bob Duronio lab) published an article titled “Direct interrogation of the role of H3K9 in metazoan heterochromatin function” in Genes and Development 30: 1866-1880. (Image: Cover showing Drosophila polytene chromosome from an H3K9R mutant stained with antibody for H3K9me3; see article for details.) Please see our page on...

Aminah Wali (Ian Davis lab) published an article titled “High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility” in Proceedings of the National Academy of Sciences 113: 3018-23. (Image: Heat map of normalized FAIRE enrichment; see article for details.) Please see our page on Publications by GMB Students for...

Nicole Tackmann (Yanping Zhang lab) published an article titled “RPL23 links oncogenic RAS signaling to p53-mediated tumor suppression” in Cancer Research (online ahead of print). (Image: Ki-67 staining of skin tumors in mice, showing the effect of Mdm2m/m genotype; see article for details.) Please see our page on Publications by...

David Wyatt (Dale Ramsden lab) published an article titled “Essential roles for polymerase 胃-mediated end joining in the repair of chromosome breaks” in Molecular Cell (online ahead of print). (Image: Schematic showing when theta-mediated end joining is important.) Please see our page on Publications by GMB Students for more.

Noelle Romero (Steve Matson lab and Jeff Sekelsky lab) published an article titled “Biochemical activities and genetic functions of the Drosophila melanogaster Fancm helicase in DNA repair” in Genetics (online ahead of print). (Image: Mitotic crossovers in different Fancm mutants.) Please see our page on Publications by GMB Students for...

Steven McDaniel (Brian Strahl lab) published an article titled “Combinatorial histone readout by the dual plant homeodomain (PHD) fingers of Rco1 mediates Rpd3S chromatin recruitment and the maintenance of transcriptional fidelity” in Journal of Biological Chemistry 291: 14796-802. (Image: Model for how the PHD fingers in Rpd3S and Rpd3L engage...

Jordan Kardos (William Kim lab) published an article titled “Claudin-low bladder tumors are immune infiltrated and actively immune suppressed” in JCI Insight. Image: Box plot of immune suppression gene signature z scores across the Pan-Cancer tumor types. See paper for details.   Please see our page on Publications by GMB...

Li-Chung Tsao (Lishan Su lab) published an article titled “CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo” in Retrovirology 13: 22. Image: FACS plots of CD4 and CD8 staining live CD3(+) T cells infected with a highly pathogenic HIV-1 isolate....

Lauren Waldron Wasson (Frank Conlon lab) published an article titled “The cardiac TBX5 interactome reveals a chromatin remodeling network essential for cardiac septation” in Developmental Cell 36: 262-275. Image: Low-magnification transverse section of a developing Xenopus heart; see article for complete figure and details.   Please see our page on...

Tiki Hayes (Channing Der lab) published an article titled “Long-term ERK inhibition in KRAS-mutant pancreatic cancer is associated with MYC degradation and senescence-like growth suppression” in Cancer Cell 29: 75-89. Image: Treated PANC253 tumors; see article for details.   Please see our page on Publications by GMB Students for more.

Dan Serber (Terry Magnuson lab) published an article titled “The mouse INO80 chromatin remodeling complex is an essential meiotic factor for spermatogenesis” in Biology of Reproduction (epub ahead of print). Image: unrepaired DNA breaks in Ino80cKO spermatocytes; see article for details.   Please see our page on Publications by GMB...