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Talia Hatkevich (Jeff Sekelsky lab) published an article titled “Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing” in PLOS Genetics (DOI: 10.1371/journal.pgen.1008412). Image:FISH on meiotic chromosomes showing lack of pairing (two foci) despite synaptonemal complex (magenta); click in image for 3D animation; see article for details. Please see...

A new module titled CRISPR-Based Genome Engineering (GNET 760) will be offered starting in Spring 2020. The module is being taught by Hector Franco, Assistant Professor of Genetics. It will include visits by a number of 黑料网 experts in various CRISPR-based technologies. The course will meet Tuesdays and Thursdays from...

Vicki Madigan (Aravind Asokan lab) published an article titled “A CRISPR screen identifies the cell polarity determinant Crumbs 3 as an adeno-associated virus restriction factor in hepatocytes” in Journal of VIrology (DOI: 10.1128/JVI.00943-19). Image: Outline of the high-throughput CRISPR screen for AAV restriction factors; see article for details. Please see...

Rebekah Watkins-Schultz (Jenny Ting lab) published an article titled “A microparticle platform for STING-targeted immunotherapy enhances natural killer cell- and CD8+ T cell-mediated anti-tumor immunity” in Biomaterials (DOI: 10.1016/j.biomaterials.2019.03.011). Image: Flow cytometry to detect tumor-infiltrating leukocytes after microparticle injection; see article for details. Please see our page on Publications by...

Kale Hartmann (Jeff Sekelsky lab) published an article titled “Centromere-proximal meiotic crossovers in Drosophila melanogaster are suppressed by both highly repetitive heterochromatin and proximity to the centromere” in Genetics (DOI: 10.1534/genetics.119.302509).The article was chosen for Highlights by the editors.聽 Image:Relationship of genome features (gene and TE density) to crossover density...

David Lee (Mauro Calabrese lab) published a paper titled “A 5′ fragment of Xist can sequester RNA produced from adjacent genes on chromatin“ in Nucleic Acids Research (DOI:10.1093/nar/gkz432). GMB students Rachel Cherney and Megan Schertzer are co-authors. Image: The TETRIS reporter demonstrates that Xist-2kb represses luciferase at the post-transcriptional level;...

Claire Trincot (Kathleen Caron lab) published a paper titled “Adrenomedullin induces cardiac lymphangiogenesis after myocardial infarction and regulates cardiac edema via connexin 43“ in Circulation Research (DOI:10.1161/CIRCRESAHA.118.313835). Image: Immunohistochemistry of cardiac sections in infarcted adult Adm+/+ and Admhi/hi mice; see article for details. See also the commentary on this article:...

Lauren Donoghue (Samir Kelada lab) has been selected to attend the Leena Peltonen School of Human Genomics program in Switzerland in August. Graduate and postdoctoral trainees gather with leading experts in the field for interactive discussions and presentations on cutting-edge topics in human genetics and genomics. Participants also receive one-to-one...

Kale Hartmann and Talia Hatkevich (Jeff Sekelsky lab) published an article titled “Meiotic MCM proteins promote and inhibit crossovers during meiotic recombination.” in Genetics (DOI: 10.1534/genetics.119.302221). Image:Schematic of meiotic MCM protein structures; see article for details. Please see our page on Publications by GMB Students for more.

Lauren Donoghue (Samir Kelada lab) was selected for a DeLill Nasser Award for Professional Development in Genetics from the Genetics Society of America. Talia will use the award to travel to the Drosophila Research Conference where she has been selected to give a talk.   Please also see our page...

Brea Hampton (co-mentored by Mark Heise and Marty Ferris) was selected to receive a Gilliam Fellowship for Advanced Study from the Howard Hughes Medical Institute. The goal of the program is “to increase the diversity among scientists who are prepared to assume leadership roles in science, particularly as college and...

Kia Perez-Vale (Mark Peifer lab) was awarded an NRSA F31 fellowship from NIH’s National Institute for General Medical Sciences. Kia’s project is titled “Defining the molecular mechanisms underlying apical-basal polarity establishment and morphogenesis.”聽 (Photo: Kia received the funding notification while participating in the Gordon Research Conference on Cell Contact and...