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Ann Emery (Ron Swanstrom lab) published an article titled “Characterizing HIV-1 splicing using next generation sequencing” in Journal of Virology (DOI:10.1128/JVI.02515-16). Image: Splicing in founder and transmittend HIV-1 (click to enlarge; see article for details). Please see our page on Publications by GMB Students for more.

Greg Zapotoczny (Jeff Sekelsky lab) published an article titled “Human cell assays for synthesis-dependent strand annealing and crossing over during double-strand break repair” in G3: Genes|Genomes|Genetics (DOI:10.1534/g3.116.037390). Image: U2OS cells expression GFP (crossover) or GFP and mCherry (non-crossover) after double-strand break repair; see article for details. Please see our page...

Mira Pronobis (Mark Peifer lab) published an article titled “Reconstituting regulation of the canonical Wnt pathway by engineering a minimal 尾-catenin destruction machine” in Molecular Biology of the Cell (DOI:10.1091/mbc.E16-07-0557). Image: Superesolution microscopy (SIM) showing assembly into supermolecular puncta of Axin alone, Axin plus APC or the a designed chimera;...

Bailey Peck (Praveen Sethupathy聽lab) published an article titled “Functional transcriptomics in diverse intestinal epithelial cell types reveals robust microRNA sensitivity in intestinal stem cells to microbial status” in Journal of Biological Chemistry (DOI:10.1074/jbc.M116.770099). Bailey’s paper was featured in an article from the 黑料网 Newsroom.聽 Image: Model of miR-375-3p-mediated effects of...

Talia Hatkevich (Jeff Sekelsky lab) and Kathryn Kohl (former GMB student, currently Assistant Professor at Winthrop University) published an article titled “Bloom syndrome helicase promotes meiotic crossover patterning and homolog disjunction” in Current Biology (DOI:10.1016/j.cub.2016.10.055), highlighted in a Dispatch. GMB student Michaelyn Hartmann was a co-author. Image: Graphical abstract showing...

Mike Conlin (Dale Ramsden lab) was awarded an NRSA F31 fellowship from the National Cancer Institute. The title of his project is “Mechanism of Damage Tolerance by Nonhomologous End Joining.“ Please also see our page on Grants to GMB Students.

Christian Parobek (Jonathon Juliano lab) published an article titled “Selective sweep suggests transcriptional regulation may underlie Plasmodium vivax resilience to malaria control measures in Cambodia” in Proceedings of the National Academy of Sciences (Early Edition). Image: Manhattan plot of sites under strong selection; see article for details. Please see our...

Christian Parobek (Jonathon Juliano lab) published an article titled “skelesim: an extensible, general framework for population genetic simulation in R” in Molecular Ecology Resources. Image: Output from skelesim simulations. See article for details. Please see our page on Publications by GMB Students for more.

Congratulations to GMB faculty member Dr Amy Gladfelter (Department of Biology), who has been named a聽Howard Hughes Medical Institute (HHMI) Faculty Scholar. This designation is awarded to early-career scientists who have great potential to make unique contributions to their field. Dr. Gladfelter’s research focuses on how multinucleate cells are organized...

Catherine Fahey (Kim Rathmell and Ian Davis labs) and Julia DiFiore (Brian Strahl lab) published an article titled “Structure/function analysis of recurrent mutations in SETD2 reveals a critical and conserved role for a SET domain residue in maintaining protein stability and H3K36 trimethylation” in Journal of Biology Chemistry (online ahead...

Taylor Penke (Bob Duronio lab) published an article titled “Direct interrogation of the role of H3K9 in metazoan heterochromatin function” in Genes and Development 30: 1866-1880. (Image: Cover showing Drosophila polytene chromosome from an H3K9R mutant stained with antibody for H3K9me3; see article for details.) Please see our page on...

Aminah Wali (Ian Davis lab) published an article titled “High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility” in Proceedings of the National Academy of Sciences 113: 3018-23. (Image: Heat map of normalized FAIRE enrichment; see article for details.) Please see our page on Publications by GMB Students for...