{"id":2970,"date":"2016-10-24T19:17:33","date_gmt":"2016-10-24T23:17:33","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/directory\/william-valdar-phd\/"},"modified":"2025-04-15T14:12:11","modified_gmt":"2025-04-15T18:12:11","slug":"william-valdar-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/genetics\/directory\/william-valdar-phd\/","title":{"rendered":"William Valdar, PhD"},"content":{"rendered":"<p><!-- description --><\/p>\n<h2>Research Interests<\/h2>\n<p><strong class=\"keywords\">Keywords:\u00a0Mapping of complex disease loci in animal models, statistical genetics<\/strong><\/p>\n<p>I run a statistical genetics lab interested the relationship between genes and complex disease. In particular, we are interested in animal models of multifactorial human disease, including cancer susceptibility, diabetes and anxiety disorders and how these are affected by genetic variation. Our current research topics are:<\/p>\n<p>1) Development of statistical methods for modeling the effect of genetic variation on comorbid disease traits.<br \/>\n2) Development of methods for characterizing statistical uncertainty of multiple QTL models due to population structure, finite sample size, confounding<br \/>\nenvironment and uncertainty in genetic causal state.<br \/>\n3) Hierarchical modeling of multivariate phenotypes in animal models.<br \/>\n4) Design of mouse resource populations for linkage disequilibrium mapping.<\/p>\n<p>We currently focus on the use of outbred and recombinant inbred populations of rodents such as the Heterogeneous Stock (HS) mice, HS rats, the Collaborative Cross, Advanced Intercross Lines and derived populations, and collaborate extensively with experimental groups in the analysis of such populations.<\/p>\n<h2>Mentor Training:<\/h2>\n<ul>\n<li>Everfi Course &#8211; Harrassment and Discrimination Prevention<\/li>\n<li>Faculty Mentoring Workshop for Biomedical Researchers<\/li>\n<li>Mental Health First Aid<\/li>\n<\/ul>\n<h2>Publications<\/h2>\n<p><strong><span class=\"largeFont\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?cmd=PureSearch&amp;db=pubmed&amp;term=Valdar-W[AU]\">PubMed Link<\/a><\/span><\/strong><\/p>\n<p><strong><span class=\"largeFont\"><a href=\"http:\/\/www.experts.scival.com\/reachnc\/expertPubs.asp?n=William+Seth+Valdar&amp;u_id=5002953\">Link to Publications on Reach NC site<\/a><\/span><\/strong><\/p>\n<h2>William Valdar in 黑料网 Genetics News<\/h2>\n            <div class=\"wc-cards\"><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-june-9th-22nd-2024\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">June 24, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for June 9th &#8211; 22nd, 2024<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 12 papers during June 9th - 22nd 2024.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for June 9th &#8211; 22nd, 2024\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-may-12th-june-8th-2024\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">June 10, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for May 12th &#8211; June 8th, 2024<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 23 papers during May 12th - June 8th 2024.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for May 12th &#8211; June 8th, 2024\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-september-24th-october-7th-2023\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">October 9, 2023<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for September 24th &#8211; October 7th, 2023<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 12 papers during September 24th - October 7th 2023.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for September 24th &#8211; October 7th, 2023\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-june-4th-17th-2023\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">June 19, 2023<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for June 4th &#8211; 17th, 2023<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 10 papers during June 4th - 17th, 2023.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for June 4th &#8211; 17th, 2023\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/beltran-perou-and-valdar-recognized-with-awards-for-excellence-in-basic-science-mentoring\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2023\/02\/Beltran-Perou-and-Valdar-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"Beltran Perou and Valdar\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2023\/02\/Beltran-Perou-and-Valdar-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2023\/02\/Beltran-Perou-and-Valdar-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">February 28, 2023<\/p><h3 class=\"wc-card__title wc-card__title--3\">Beltran, Perou and Valdar Recognized with Awards for Excellence in Basic Science Mentoring<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">The Office of Graduate Education has recognized three Genetics faculty members with Mentoring Awards.\u00a0<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Beltran, Perou and Valdar Recognized with Awards for Excellence in Basic Science Mentoring\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-october-9th-22nd-2022\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">October 24, 2022<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for October 9th \u2013 22nd, 2022<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 10 papers during October 9th\u00a0\u2013 22nd, 2022.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for October 9th \u2013 22nd, 2022\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/rachel-dumez-gmb-and-ellen-risemberg-bcb-selected-top-ten-for-three-minute-thesis\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2022\/10\/Rachel-Dumez-and-Ellen-Risemberg-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"Rachel Dumez and Ellen Risemberg\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2022\/10\/Rachel-Dumez-and-Ellen-Risemberg-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2022\/10\/Rachel-Dumez-and-Ellen-Risemberg-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">October 6, 2022<\/p><h3 class=\"wc-card__title wc-card__title--3\">Rachel DuMez (GMB) and Ellen Risemberg (BCB) selected top ten for Three Minute Thesis<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Congratulation to Rachel DuMez, Genetics and Molecular Biology Graduate Student, and Ellen Risemberg, Bioinformatics and Computational Biology Graduate Student, who were both selected in the top ten for Three Minute Thesis!<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Rachel DuMez (GMB) and Ellen Risemberg (BCB) selected top ten for Three Minute Thesis\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-may-8th-21st-2022\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">May 23, 2022<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications May 8th \u2013 21st, 2022<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 14 papers during May 8th \u2013 21st, 2022.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications May 8th \u2013 21st, 2022\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-april-24th-may-7th-2022\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">May 9, 2022<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications April 24th \u2013 May 7th, 2022<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 14 papers during April 24th\u00a0\u2013 May 7th, 2022.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications April 24th \u2013 May 7th, 2022\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-december-12th-2021-january-1st-2022\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">January 3, 2022<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications December 12th, 2021 \u2013 January 1st, 2022<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 14 papers during\u00a0December 12th, 2021 \u2013 January 1st,\u00a02022.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications December 12th, 2021 \u2013 January 1st, 2022\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article>            <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Research Interests Keywords:\u00a0Mapping of complex disease loci in animal models, statistical genetics I run a statistical genetics lab interested the relationship between genes and complex disease. In particular, we are interested in animal models of multifactorial human disease, including cancer susceptibility, diabetes and anxiety disorders and how these are affected by genetic variation. Our current &hellip; <a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-december-12th-2021-january-1st-2022\/\" aria-label=\"Read more about Department of Genetics Publications December 12th, 2021 \u2013 January 1st, 2022\">Read more<\/a><\/p>\n","protected":false},"featured_media":9774,"template":"","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"class_list":["post-2970","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>William Valdar, PhD | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/directory\/william-valdar-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"William Valdar, PhD | Department of Genetics\" \/>\n<meta property=\"og:description\" content=\"Research Interests Keywords:\u00a0Mapping of complex disease loci in animal models, statistical genetics I run a statistical genetics lab interested the relationship between genes and complex disease. In particular, we are interested in animal models of multifactorial human disease, including cancer susceptibility, diabetes and anxiety disorders and how these are affected by genetic variation. 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