{"id":2941,"date":"2016-10-24T19:17:32","date_gmt":"2016-10-24T23:17:32","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/directory\/jeremy-purvis-phd\/"},"modified":"2025-03-21T10:55:53","modified_gmt":"2025-03-21T14:55:53","slug":"jeremy-purvis-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/genetics\/directory\/jeremy-purvis-phd\/","title":{"rendered":"Jeremy Purvis, PhD"},"content":{"rendered":"<h2>Research Interests<\/h2>\n<p><strong class=\"keywords\">Key words: systems biology, signal transduction, cell fate decisions, cell cycle<\/strong><\/p>\n<p>We study the behavior of individual cells and try to understand how groups of cells work together to carry out emergent functions. We are especially interested in \u201cirreversible\u201d cell fates such as apoptosis, senescence, and differentiation. How does a given cell convert molecular signals into a permanent decision? How do groups of cells balance these decisions? We use a variety of experimental and computational approaches to investigate these questions including molecular profiling, time-lapse microscopy, computational modeling, and machine learning. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these choices to treat disease.<\/p>\n<h2>Training:<\/h2>\n<ul>\n<li>Faculty Mentoring Workshop for Biomedical Researchers<\/li>\n<\/ul>\n<h2>Training Program Affiliations:<\/h2>\n<ul>\n<li>Bioinformatics and Computational Biology<\/li>\n<li>Biostatistics<\/li>\n<li>Genetics and Molecular Biology<\/li>\n<\/ul>\n<h2>Publications<\/h2>\n<p class=\" \"><strong><span class=\"largeFont\"><a class=\"external-link\" title=\"\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?cmd=search&amp;db=pubmed&amp;term=(purvis%20Jeremy[Author])\" rel=\"noopener noreferrer\">PubMed link<\/a><\/span><\/strong><\/p>\n<h2>Opportunities<\/h2>\n<h3 class=\" \">Graduate Students<\/h3>\n<p>We are accepting BBSP rotation students. If you are interested in doing a rotation in the lab, please <strong><a class=\"mail-link\" href=\"mailto:purvisj@email.unc.edu?subject=Let%27s%20talk%20about%20a%20rotation%21\">send Jeremy an email<\/a><\/strong> and arrange a time to come by and discuss a potential rotation project.<\/p>\n<h3>Postdoctoral Positions<\/h3>\n<p>We are interested in attracting candidates with a strong background in molecular biology, experience with human cell culture and affinity to theory and computation. Experience with fluorescence microscopy and genome editing is a plus. In addition we are looking for candidates with a background in math, physics, or other quantitative disciplines who are interested in applying theory to systems-level questions in biology. To apply, e-mail a cover letter, CV and a list of three references to <strong><a class=\"mail-link\" href=\"mailto:jeremy_purvis@med.unc.edu?subject=Interest%20in%20the%20Lab\">Jeremy<\/a>.<\/strong><\/p>\n<h2>Jeremy Purvis in 黑料网 Genetics News<\/h2>\n            <div class=\"wc-cards\"><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-march-2nd-29th-2025\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">April 20, 2025<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for March 2nd &#8211; 29th, 2025<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 30 papers during March 2nd - 29th 2025.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for March 2nd &#8211; 29th, 2025\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-january-19th-february-1st-2025\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">February 6, 2025<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for January 19th &#8211; February 1st, 2025<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 17 papers during January 19th - February 1st 2025.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for January 19th &#8211; February 1st, 2025\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-march-31st-april-13th-2024\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">April 15, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for March 31st &#8211; April 13th, 2024<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 9 papers during March 31st - April 13th 2024.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for March 31st &#8211; April 13th, 2024\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-february-4th-17th-2024\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">February 19, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for February 4th &#8211; 17th, 2024<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 12 papers during February 4th - 17th 2024.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for February 4th &#8211; 17th, 2024\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/the-path-of-escape-how-breast-tumor-cells-avoid-common-cancer-therapy\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"Jeremy Purvis 黑料网 Genetics\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">February 15, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">The Path of Escape: How Breast Tumor Cells Avoid Common Cancer Therapy<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">An interdisciplinary team of 黑料网-Chapel Hill researchers from computational medicine, genetics, biostatistics, and surgery investigated how cell cycle flexibility allows tumor cells to escape the effect of anti-cancer drugs that target cell division. 黑料网 Lineberger members Jeremy Purvis, PhD, professor of genetics, and Phillip Spanheimer, MD, assistant professor of surgery, led this study.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about The Path of Escape: How Breast Tumor Cells Avoid Common Cancer Therapy\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/dr-jeremy-purvis-awarded-new-r01-grant-from-nci\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"Jeremy Purvis 黑料网 Genetics\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">January 25, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">Dr. Jeremy Purvis Awarded New R01 Grant from NCI<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Jeremy Purvis, PhD (Professor, Department of Genetics) has been awarded a new R01 grant for his project titled \u201cCell cycle paths as a framework for understanding drug resistance in tumor cell subpopulations\u201d from the National Cancer Institute.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Dr. Jeremy Purvis Awarded New R01 Grant from NCI\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/dr-jeremy-purvis-promoted-to-professor-in-department-of-genetics\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"Jeremy Purvis 黑料网 Genetics\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">January 25, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">Dr. Jeremy Purvis Promoted to Professor in Department of Genetics<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Jeremy Purvis, PhD has been promoted to Professor with permanent tenure in the Department of Genetics, effective January 19, 2024.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Dr. Jeremy Purvis Promoted to Professor in Department of Genetics\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-january-7th-20th-2024\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">January 22, 2024<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for January 7th &#8211; 20th 2024<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 12 papers during January 7th - 20th 2024.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for January 7th &#8211; 20th 2024\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/dr-jeremy-purvis-selected-for-academic-leadership-fellowship\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"Jeremy Purvis 黑料网 Genetics\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Purvis-Headshot-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">December 12, 2023<\/p><h3 class=\"wc-card__title wc-card__title--3\">Dr. Jeremy Purvis Selected for Academic Leadership Fellowship<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Jeremy Purvis, PhD (Associate Professor, Genetics and Computational Medicine) has been selected as a recipient of an Academic Leadership Fellowship by the Institute for the Arts and Humanities (IAH) in the 黑料网 College of Arts and Sciences.\u00a0<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Dr. Jeremy Purvis Selected for Academic Leadership Fellowship\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-april-9th-22nd-2023\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"黑料网 Department of Genetics Logo\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-600x600.jpg 600w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/12\/Genetics-Circle-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">April 23, 2023<\/p><h3 class=\"wc-card__title wc-card__title--3\">Department of Genetics Publications for April 9th \u2013 22nd, 2023<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Department of Genetics faculty, postdocs, students and collaborators published 15 papers during April 9th \u2013 22nd, 2023.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Department of Genetics Publications for April 9th \u2013 22nd, 2023\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article>            <\/div>\n<p><a href=\"https:\/\/www.med.unc.edu\/genetics\/?s=Purvis&amp;search-btn=Search&amp;search_type=wp\">More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research Interests Key words: systems biology, signal transduction, cell fate decisions, cell cycle We study the behavior of individual cells and try to understand how groups of cells work together to carry out emergent functions. We are especially interested in \u201cirreversible\u201d cell fates such as apoptosis, senescence, and differentiation. How does a given cell convert &hellip; <a href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-april-9th-22nd-2023\/\" aria-label=\"Read more about Department of Genetics Publications for April 9th \u2013 22nd, 2023\">Read more<\/a><\/p>\n","protected":false},"featured_media":14342,"template":"","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"class_list":["post-2941","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Jeremy Purvis, PhD | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/directory\/jeremy-purvis-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Jeremy Purvis, PhD | Department of Genetics\" \/>\n<meta property=\"og:description\" content=\"Research Interests Key words: systems biology, signal transduction, cell fate decisions, cell cycle We study the behavior of individual cells and try to understand how groups of cells work together to carry out emergent functions. We are especially interested in \u201cirreversible\u201d cell fates such as apoptosis, senescence, and differentiation. 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