Dr. Greg Smith (Assistant Professor, Genetics) and Dr. Samir Kelada (Associate Professor, Genetics)

Dr. Greg Smith (Assistant Professor, Genetics) and Dr. Samir Kelada (Associate Professor, Genetics) recently published a paper titled “A new mouse model for ozone health effects research” in Environmental Health Perspectives.

Drs. Smith and Kelada’s work identifies a strain of the Collaborative Cross (CC) mouse population as a new and improved model system to study the effects of acute and repeated exposure to ambient air pollutant ozone (O₃). Our population is experiencing increasing exposure to O_3,  and O₃ exposure is associated with adverse respiratory health outcomes. Understanding the mechanisms for how O₃ exposure results in adverse pulmonary health is critical to prevention strategies and development of treatments. Experiments outlined in this paper show that the new CC mouse model overcomes some of the limitations of existing rodent models, specifically enhanced sensitivity, and more human-like thermoregulatory response. Future studies utilizing this model system provide an opportunity to characterize the mechanisms by which exposure to O₃ causes adverse health effects.

The full paper can be found .

The post Drs. Smith and Kelada publish a new paper in Environmental Health Perspectives appeared first on Department of Genetics.

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Nat Genet. 2025 May 13. doi: 10.1038/s41588-025-02189-z. Online ahead of print.

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Halvorsen MW.

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Zannas AS.

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PMID: 40354452 No abstract available.

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McInnis MG, Coleman B, Hurwitz E, Robinson PN, Williams AE, Haendel MA, McMurry JA.

Biol Psychiatry. 2025 May 23:S0006-3223(25)01213-2. doi: 10.1016/j.biopsych.2025.05.014. Online ahead of print.

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The post Department of Genetics Publications for April 27th – May 31st, 2025 appeared first on Department of Genetics.

Dr. Melissa Haendel (Distinguished Professor, Genetics) and Dr. Eric Hurwitz (Postdoctoral Fellow)

Dr. Eric Hurwitz, postdoctoral fellow in the laboratory of Dr. Melissa Haendel (Distinguished Professor, Genetics), is the first author on a titled “Unlocking the potential of wear time of a wearable device to enhance postpartum depression screening and detection: cross-sectional study”, published in the journal JMIR Formative Research.

Using the All of Us Research Program dataset, the study demonstrated a strong trend that females with postpartum depression (PPD) wore their Fitbits more than those without PPD, leading the team to hypothesize that increased Fitbit wear time among females with PPD may be attributed to hypervigilance.  Future studies will focus on combining wear time patterns with digital biomarkers such as sleep and physical activity to enhance early PPD detection using machine learning.

The post Haendel Lab Publishes New Paper in JMIR Formative Research appeared first on Department of Genetics.

Lauryn Bailey

Lauryn Bailey (Biology ’25) will join the first cohort of students in the ������’s newly created Postbaccalaureate Research Initiative in Science and Medicine (PRISM) program this summer.

She will work with Genetics faculty Phil Spanheimer, Sam Wolff, and Jeremy Purvis to study mechanisms of resistance in liposarcomas using single-cell imaging approaches.

The post Lauryn Bailey joins ������’s Postbaccalaureate Research Initiative in Science and Medicine (PRISM) program this summer appeared first on Department of Genetics.

Kent TV, Schrider DR, Matute DR.

Genome Biol Evol. 2025 Apr 4:evaf066. doi: 10.1093/gbe/evaf066. Online ahead of print.

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Nagarajan P, Winkler TW, Bentley AR, Miller CL, Kraja AT, Schwander K, Lee S, Wang W, Brown MR, Morrison JL, Giri A, O’Connell JR, Bartz TM, de Las Fuentes L, Gudmundsdottir V, Guo X, Harris SE, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer ND, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most PJ, Wang Y, Weiss S, Westerman KE, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja AD, Arzt M, Aschard H, Attia JR, Bazzanno L, Breyer MA, Brody JA, Cade BE, Chen HH, Chen YI, Chen Z, de Vries PS, Dimitrov LM, Do A, Du J, Dupont CT, Edwards TL, Evans MK, Faquih T, Felix SB, Fisher-Hoch SP, Floyd JS, Graff M, Gu C, Gu D, Hairston KG, Hanley AJ, Heid IM, Heikkinen S, Highland HM, Hood MM, Kähönen M, Karvonen-Gutierrez CA, Kawaguchi T, Kazuya S, Kelly TN, Komulainen P, Levy D, Lin HJ, Liu PY, Marques-Vidal P, McCormick JB, Mei H, Meigs JB, Menni C, Nam K, Nolte IM, Pacheco NL, Petty LE, Polikowsky HG, Province MA, Psaty BM, Raffield LM, Raitakari OT, Rich SS, Riha RL, Risch L, Risch M, Ruiz-Narvaez EA, Scott RJ, Sitlani CM, Smith JA, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, Willems van Dijk K, Wilson OD, Xia R, Yao J, Young KL, Zhang R, Zhu X, Below JE, Böger CA, Conen D, Cox SR, Dörr M, Feitosa MF, Fox ER, Franceschini N, Gharib SA, Gudnason V, Harlow SD, He J, Holliday EG, Kutalik Z, Lakka TA, Lawlor DA, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison AC, Penninx BW, Peyser PA, Rotter JI, Snieder H, Spector TD, Wagenknecht LE, Wareham NJ, Zonderman AB, North KE, Fornage M; Million Veteran Program; Hung AM, Manning AK, Gauderman J, Chen H, Munroe PB, Rao DC, van Heemst D, Redline S, Noordam R, Wang H.

Mol Psychiatry. 2025 Apr 4. doi: 10.1038/s41380-025-02954-w. Online ahead of print.

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Nguyen VL, Eick KL, Gan M, Miner TA, Friedland AE, Carey AF, Olivier KN, Liu Q.

JAC Antimicrob Resist. 2025 Apr 2;7(2):dlaf047. doi: 10.1093/jacamr/dlaf047. eCollection 2025 Apr.

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Hu Y, Haessler J, Lundin JI, Darst BF, Whitsel EA, Grove M, Guan W, Xia R, Szeto M, Raffield LM, Ratliff S, Wang Y, Wang X, Fohner AE, Lynch MT, Patel YM, Lani Park S, Xu H, Mitchell BD, Bis JC, Sotoodehnia N, Brody JA, Psaty BM, Peloso GM, Tsai MY, Rich SS, Rotter JI, Smith JA, Kardia SLR, Reiner AP, Lange L, Fornage M, Pankow JS, Graff M, North KE, Kooperberg C, Peters U.

Clin Epigenetics. 2025 Apr 2;17(1):54. doi: 10.1186/s13148-025-01859-3.

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Van Alsten SC, Love MI, Calhoun BC, Butler EN, Perou CM, Hoadley KA, Troester MA.

Cancer Res. 2025 Apr 3;85(7):1327-1340. doi: 10.1158/0008-5472.CAN-24-1788.

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Bruxel EM, Rovaris DL, Belangero SI, Chavarría-Soley G, Cuellar-Barboza AB, Martínez-Magaña JJ, Nagamatsu ST, Nievergelt CM, Núñez-Ríos DL, Ota VK, Peterson RE, Sloofman LG, Adams AM, Albino E, Alvarado AT, Andrade-Brito D, Arguello-Pascualli PY, Bandeira CE, Bau CHD, Bulik CM, Buxbaum JD, Cappi C, Corral-Frias NS, Corrales A, Corsi-Zuelli F, Crowley JJ, Cupertino RB, da Silva BS, De Almeida SS, De la Hoz JF, Forero DA, Fries GR, Gelernter J, González-Giraldo Y, Grevet EH, Grice DE, Hernández-Garayua A, Hettema JM, Ibáñez A, Ionita-Laza I, Lattig MC, Lima YC, Lin YS, López-León S, Loureiro CM, Martínez-Cerdeño V, Martínez-Levy GA, Melin K, Moreno-De-Luca D, Muniz Carvalho C, Olivares AM, Oliveira VF, Ormond R, Palmer AA, Panzenhagen AC, Passos-Bueno MR, Peng Q, Pérez-Palma E, Prieto ML, Roussos P, Sanchez-Roige S, Santamaría-García H, Shansis FM, Sharp RR, Storch EA, Tavares MEA, Tietz GE, Torres-Hernández BA, Tovo-Rodrigues L, Trelles P, Trujillo-ChiVacuan EM, Velásquez MM, Vera-Urbina F, Voloudakis G, Wegman-Ostrosky T, Zhen-Duan J, Zhou H; Latin American Genomics Consortium; Santoro ML, Nicolini H, Atkinson EG, Giusti-Rodríguez P, Montalvo-Ortiz JL.

Nat Genet. 2025 Apr 2. doi: 10.1038/s41588-025-02127-z. Online ahead of print.

PMID: 40175716����𱹾����.

Aseem F, Fink E, Liu C, Whalen J, Werdel J, Nanavati P, Zou F, Wabulya A, Olm-Shipman C, LaRoche SM, Rubinos C.

Neurol Clin Pract. 2025 Jun;15(3):e200464. doi: 10.1212/CPJ.0000000000200464. Epub 2025 Mar 31.

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Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NS, Meyer M, Gupta S, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Le Marchand L, McDonald MN, McHugh CP, Morrison AC, Naseri T; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; O’Connell J, O’Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Ida Chen YD, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Benjamin Shoemaker M, Smith NL, Taylor KD, Telen MJ, Weiss ST, Zhang Y, Heard-Costa N, Sun YV, Lin X, Cupples LA, Lange LA, Liu CT, Loos RJF, North KE, Justice AE.

Nat Commun. 2025 Apr 11;16(1):3470. doi: 10.1038/s41467-025-58420-2.

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Huang YN, Munteanu V, Love MI, Ronkowski CF, Deshpande D, Wong-Beringer A, Corbett-Detig R, Dimian M, Moore JH, Garmire LX, Reddy TBK, Butte AJ, Robinson MD, Eskin E, Abedalthagafi MS, Mangul S.

Cell Genom. 2025 Apr 8:100845. doi: 10.1016/j.xgen.2025.100845. Online ahead of print.

PMID: 40215974����𱹾����.

Petty LE, Chen HH, Frankel EG, Zhu W, Downie CG, Graff M, Lin P, Sharma P, Zhang X, Scartozzi AC, Roshani R, Landman JM, Boehnke M, Bowden DW, Chambers JC, Mahajan A, McCarthy MI, Ng MCY, Sim X, Spracklen CN, Zhang W, Preuss M, Bottinger EP, Nadkarni GN, Loos RJF, Chen YI, Tan J, Ipp E, Genter P, Emery LS, Louie T, Sofer T, Stilp AM, Taylor KD, Xiang AH, Buchanan TA, Roll K, Gao C, Palmer ND, Norris JM, Wagenknecht LE, Nousome D, Varma R, McKean-Cowdin R, Guo X, Hai Y, Hsueh W, Sandow K, Parra EJ, Cruz M, Valladares-Salgado A, Wacher-Rodarte N, Rotter JI, Goodarzi MO, Rich SS, Bertoni A, Raffel LJ, Nadler JL, Kandeel FR, Duggirala R, Blangero J, Lehman DM, DeFronzo RA, Thameem F, Wang Y, Gahagan S, Blanco E, Burrows R, Huerta-Chagoya A, Florez JC, Tusie-Luna T, González-Villalpando C, Orozco L, Haiman CA, Hanis CL, Rohde R, Whitsel EA, Reiner AP, Kooperberg C, Li Y, Duan Q, Lee M, Correa-Burrows P, Fried SK, North KE, McCormick JB, Fisher-Hoch SP, Gamazon ER, Morris AP, Mercader JM, Highland HM, Below JE; DIAMANTE Hispanic/Latino Consortium; Global Hispanic Lipids Consortium.

Nat Commun. 2025 Apr 11;16(1):3438. doi: 10.1038/s41467-025-58574-z.

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Kharitonova EV, Sun Q, Ockerman F, Chen B, Zhou LY, Hysong MR, Tuftin B, Cao H, Mathias RA, Auer PL, Ober C, Raffield LM, Reiner AP, Cox NJ, Kelada SNP, Tao R, Li Y.

Am J Hum Genet. 2025 Apr 3:S0002-9297(25)00107-7. doi: 10.1016/j.ajhg.2025.03.008. Online ahead of print.

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Harigaya Y, Matoba N, Le BD, Valone JM, Stein JL, Love MI, Valdar W.

PLoS Genet. 2025 Apr 9;21(4):e1011561. doi: 10.1371/journal.pgen.1011561. Online ahead of print.

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Zhang X, Scadden AW, Marthi A, Buchanan VL, Qu Y, Ferrier KR, Chen BD, Graff M, Avila J, Boerwinkle E, Buyske S, Clish CB, Cruz D, Fornage M, Gerzsten RE, Gignoux CR, Glover L, Hou L, Justice AE, Kooperberg C, Kramer H, Lange L, Loos RJF, Matise T, Mychaleckyj JC, Olabisi OA, Peters U, Raffield LM, Reiner AP, Rich SS, Rotter JI, Taylor KD, Yu B, Zheng Y, North KE, Mottl AK, Highland HM, Stanislawski MA.

J Am Soc Nephrol. 2025 Apr 7. doi: 10.1681/ASN.0000000688. Online ahead of print.

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Sun Q, Horimoto ARVR, Chen B, Ockerman F, Mohlke KL, Blue E, Raffield LM, Li Y.

Am J Hum Genet. 2025 Apr 3;112(4):727-740. doi: 10.1016/j.ajhg.2025.03.004.

PMID: 40185073����𱹾����.

Lynch WB, Miracle SA, Goldstein SI, Beierle JA, Bhandari R, Gerhardt ET, Farnan A, Nguyen BM, Wingfield KK, Kazerani I, Saavedra GA, Averin O, Baskin BM, Ferris MT, Reilly CA, Emili A, Bryant CD.

J Pharmacol Exp Ther. 2025 Mar 21;392(5):103557. doi: 10.1016/j.jpet.2025.103557. Online ahead of print.

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Storch EA, Cheng JS, Higham M, Muñoz JS, Cruz VZ, Berrones D, Obando DP, Anderberg JL, Frederick RM, Tapia-Cuevas V, Muñoz MC, Villar CU, Moya PR, Ochoa-Panaifo ME, Mallen MCM, Wiese AD, Pinciotti CM, Sagarnaga MN, McGuire JF, Onyeka OC, Moyano MB; Latin American Trans-Ancestry INitiative for OCD genomics (LATINO); Brazilian Obsessive-Compulsive Spectrum Disorder Working Group (GTTOC); Goodman WK, Crowley JJ.

Psychiatry Res. 2025 Apr 5;348:116456. doi: 10.1016/j.psychres.2025.116456. Online ahead of print.

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Yin W, Li T, Wu Z, Hung SC, Hu D, Gui Y, Cho S, Sun Y, Woodburn MA, Wang L, Li G, Piven J, Elison JT, Wu CW, Zhu H, Cohen JR, Lin W; ������/UMN Baby Connectome Project Consortium.

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PMID: 40255155 No abstract available.

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Jiang Y, Zhao B, Wang X, Tang B, Peng H, Luo Z, Shen Y, Wang Z, Jiang Z, Wang J, Ye J, Wang X, Zhu H.

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Grossman RL, Vinson J, Bain E, Bisselou K, Chandan S, Compton C, Hu J, Johann DJ, Jones F, Jones G, LeBlang S, Lee JSH, Lichtenberg T, Lockwood CM, Lyle J, Martini JF, Merker JD, Saunders L, Scher H, Somiari S, You J, Leiman LC.

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The post Department of Genetics Publications for March 30th – April 26th, 2025 appeared first on Department of Genetics.

The ������ has named three outstanding researchers as recipients of the eighth annual Yang Family Biomedical Scholars Award!

They are: Gaorav Gupta, MD, PhD, associate professor of Radiation Oncology and member of ������ Lineberger Comprehensive Cancer Center; Misty Good, MD, MS, associate professor of Pediatrics and Chief of the Division of Neonatal-Perinatal Medicine; and Jason Stein, PhD, associate professor of Genetics and member of the ������ Neuroscience Center.

Each faculty member will receive a generous grant to be used at their discretion for biomedical research projects at the ������. The researchers are now members of the Yang Family Society of Biomedical Scholars, which will host its annual seminar to highlight their work later this summer. The awards were made possible through donations from Yuanqing Yang, Chairman and CEO of Lenovo, with additional financial support from Mr. To Hing Wu, an associate to Mr. Yang.

“We are extremely grateful for Mr. Yang and Mr. Wu’s continued support of our School of Medicine’s research mission,” said Blossom Damania, PhD, Vice Dean for Research at the ������. “Their generous support has catalyzed the research of our Yang Scholars, who are working at the forefront of the most pressing biomedical research questions.”

With the Yang Scholars program, the ������ has established a community of dedicated, promising young tenured faculty. The award recognizes faculty that have made significant scholarly contributions to their field while also receiving national recognition for their research.

 research interest is to understand the interplay between genome integrity pathways and breast cancer initiation, progression, and response to therapy. He has made seminal contributions to the understanding of the genetic mechanisms that underlie tissue-specific metastasis of breast cancer. At ������, Dr. Gupta has established a vigorous research laboratory that aims to understand how DNA repair programs are reconfigured during cancer pathogenesis. The underlying focus of his work is the recognition that our normal cells routinely suffer a large number of DNA mutations, and that we have evolved an impressive array of DNA-repair mechanisms to “fix” these mutations.

Dr. Gupta’s laboratory also uncovered a mechanism by which DNA damage activates the innate immune system. His team demonstrated that this process involves direct collaboration between the canonical DNA repair protein Mre11 and the immune sensor cGAS, previously recognized for detecting viral DNA. As a physician-scientist, Dr. Gupta has successfully translated these mechanistic insights into novel therapeutic strategies for cancer patients.

Dr. Good’s laboratory is focused on the cellular and molecular mechanisms involved in the pathogenesis of a devastating intestinal disease primarily affecting premature infants called necrotizing enterocolitis (NEC). The long-term goal of the Good Lab is to understand the signaling pathways regulating the uncontrolled immune response in NEC and how these responses can be prevented through dietary modifications or targeted intestinal epithelial therapies. She uses a creative, multi-faceted approach in her research that combines pre-clinical animal studies, novel in vitro models, along with multi-omic analysis of patient samples.

In addition, Dr. Good has developed an innovative in vitro model of NEC, called “NEC-on-a-Chip,” using a microfluidic device, human neonatal intestinal enteroids, and the microbiome of infants with NEC as a pre-clinical model to test drugs on premature human intestine. In her translational research studies, she is actively working to identify a biomarker for NEC. To accomplish this, while Dr. Good was a junior faculty member, she founded and developed the infrastructure for the NEC Biorepository, which has grown into a ten-center collaborative effort incorporating biological samples and clinical data from premature infants across the country. Her basic and translational research utilizes a bench-to-bedside approach with multiple cutting-edge techniques.

Dr. Stein’s research explores how variations in the genome change the structure and development of the brain, and in doing so, create risk for neuropsychiatric illness. This work identified the first highly significant and replicated common variants influencing brain structure. His lab also studies genetic control of human cortical development through the identification of genetic variants that influence the expression of nearby genes.

One of the recent cutting-edge developments in the Stein lab is the establishment of cortical organoids from induced pluripotent stem cells (IPSCs) harvested from blood samples from individuals with autism and those without. These organoids are used to understand the cellular and molecular mechanisms leading to brain overgrowth in individuals with autism. The Stein lab has also successfully moved into new fields of study, evidenced by the awarding of a new Alzheimer’s disease U01 grant from NIA focused on modeling gene x environment interactions using the cortical organoid model.

Media contact: Brittany Phillips, Communications Specialist, ������ Health | ������

This article originally appeared in the ������ Health Newsroom .

The post ������ Names 2024-25 Yang Family Biomedical Scholars appeared first on Department of Genetics.

Dr. Wanda O’Neal (Professor, Medicine and Genetics (secondary))

Dr. Wanda O’Neal (Professor, Medicine and Genetics (secondary)) was awarded a new grant from the Cystic Fibrosis Foundation for her project titled “Hypoxia signaling: a therapeutic target for cystic fibrosis lung disease”.

The proposed research focuses on three aims: Aim 1, address the hypothesis that the chromatin in basal cells is altered by chronic hypoxia. Aim 2, explore the hypothesis that HIF1A and EPAS1 regulate specific targets independent of inflammatory signaling. Understanding the differences will guide therapeutic development. A focus on small airways will increase relevance to early CF lung disease, when targeting these pathways may be most beneficial. Aim 3, explore the hypothesis that state-of-the art hypoxia-reporter mice, combined with disease models and hypoxia signaling inhibitors, will allow exploration of therapeutic targets and disease mechanisms.

The post O’Neal Awarded Cystic Fibrosis Foundation Research Grant appeared first on Department of Genetics.

Dr. Terry Magnuson (Kay M. & Van L. Weatherspoon Eminent Distinguished Professor, Genetics and Vice Dean for Research and Strategy, School of Data Science and Society)

Dr. Terry Magnuson (Kay M. & Van L. Weatherspoon Eminent Distinguished Professor, Genetics and Vice Dean for Research and Strategy, School of Data Science and Society) is the Lead PI on the recently awarded competitive renewal of a U42 grant from the NIH Office of the Director titled “A Carolina Center to characterize and maintain mutant mice”.

Since 1999, the goal of the ������ MMRRC has been to work collectively with MMRRC consortium partners to develop and maintain high standards for importation, rederivation, cryopreservation, and distribution of mutant mouse strains to biomedical investigators and incorporate research goals that synergize with and extend the value of the resource.

The post Magnuson Renews MMRRC U42 Grant appeared first on Department of Genetics.

Dr. Anne Thessen (Associate Professor, Genetics)

Dr. Anne Thessen (Associate Professor, Genetics) was a co-author of a recently published titled “Integrating exosomes in biomedicine”.

The Perspective article resulted from her participation in the Banbury Conference on Integrating Exposomics into the Biomedical Enterprise held in December 2023.  The conference attendees crafted an operational definition of exposomics and proposed the inclusion of this data in biomedical research studies.  From the paper “the exposome is posited as an integrated compilation of all physical, chemical, biological, and (psycho) social influences that “impact biology””.  The authors proposed that gaps in our understanding of human health and disease can be filled by integrating exposomics.

The post Anne Thessen Publishes Exposomics Paper in Science appeared first on Department of Genetics.

Mandel HL, Shah SN, Bailey LC, Carton T, Chen Y, Esquenazi-Karonika S, Haendel M, Hornig M, Kaushal R, Oliveira CR, Perlowski AA, Pfaff E, Rao S, Razzaghi H, Seibert E, Thomas GL, Weiner MG, Thorpe LE, Divers J; RECOVER EHR Cohort.

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Ghoshal A, Tse EG, Hossain MA, Asressu KH, Merten EM, Sears JD, Howell S, Perveen S, Burdick J, Morales NL, Martinez SA, Law I, Davenport BJ, Morrison TE, Streblow ZJ, Streblow DN, Mordant AL, Webb TS, Cabrera A, Herring LE, Arrowsmith CH, Pearce KH, Moorman NJ, Heise MT, Couñago RM, Brown PJ, Willson TM.

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Bäckman J, Wallert J, Halvorsen M, Roelstraete B, de Schipper E, Strom NI, Eide TO, Höffler KD, Mattheisen M, Hansen B, Kvale G, Hagen K, Haavik J; Nordic OCD and Related Disorders Consortium (NORDiC); Mataix-Cols D, Rück C, Crowley JJ.

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Koulouri A, Zannas AS.

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Chen Y, Davidson NM, Wan YK, Yao F, Su Y, Gamaarachchi H, Sim A, Patel H, Low HM, Hendra C, Wratten L, Hakkaart C, Sawyer C, Iakovleva V, Lee PL, Xin L, Ng HEV, Loo JM, Ong X, Ng HQA, Wang J, Koh WQC, Poon SYP, Stanojevic D, Tran HD, Lim KHE, Toh SY, Ewels PA, Ng HH, Iyer NG, Thiery A, Chng WJ, Chen L, DasGupta R, Sikic M, Chan YS, Tan BOP, Wan Y, Tam WL, Yu Q, Khor CC, Wüstefeld T, Lezhava A, Pratanwanich PN, Love MI, Goh WSS, Ng SB, Oshlack A; SG-NEx consortium; Göke J.

Nat Methods. 2025 Mar 13. doi: 10.1038/s41592-025-02623-4. Online ahead of print.

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Sun Z, Yi Z, Wei C, Wang W, Ren T, Cravedi P, Tedla F, Ward SC, Azeloglu E, Schrider DR, Li Y, Khan A, Zanoni F, Fu J, Ali S, Liu S, Liang D, Liu T, Li H, Xi C, Vy TH, Mosoyan G, Sun Q, Kumar A, Zhang Z, Farouk S, Campell K, Ochando J, Lee K, Coca S, Xiang J, Connolly P, Gallon L, O’Connell PJ, Colvin R, Menon MC, Nadkarni G, He JC, Kraft M, Jiang X, Zhang X, Kiryluk K, Cherukuri A, Lakkis FG, Zhang W, Chen SH, Heeger PS, Zhang W.

Nat Med. 2025 Mar 10. doi: 10.1038/s41591-025-03568-z. Online ahead of print.

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Parsons VA, Vadlamudi S, Voos KM, Rohy AE, Moxley AH, Cannon ME, Rosen JD, Mills CA, Herring LE, Broadaway KA, Lorenzo DN, Mohlke KL.

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Gynecol Oncol. 2025 Mar 7;195:66-74. doi: 10.1016/j.ygyno.2025.03.003. Online ahead of print.

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Jain S, Trinidad M, Nguyen TB, Jones K, Neto SD, Ge F, Glagovsky A, Jones C, Moran G, Wang B, Rahimi K, Çalıcı SZ, Cedillo LR, Berardelli S, Özden B, Chen K, Katsonis P, Williams A, Lichtarge O, Rana S, Pradhan S, Srinivasan R, Sajeed R, Joshi D, Faraggi E, Jernigan R, Kloczkowski A, Xu J, Song Z, Özkan S, Padilla N, de la Cruz X, Acuna-Hidalgo R, Grafmüller A, Barrón LTJ, Manfredi M, Savojardo C, Babbi G, Martelli PL, Casadio R, Sun Y, Zhu S, Shen Y, Pucci F, Rooman M, Cia G, Raimondi D, Hermans P, Kwee S, Chen E, Astore C, Kamandula A, Pejaver V, Ramola R, Velyunskiy M, Zeiberg D, Mishra R, Sterling T, Goldstein JL, Lugo-Martinez J, Kazi S, Li S, Long K, Brenner SE, Bakolitsa C, Radivojac P, Suhr D, Suhr T, Clark WT.

Hum Genet. 2025 Mar 8. doi: 10.1007/s00439-025-02731-3. Online ahead of print.

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Jackson ON, Keenan TF, Nelson-Maney NP, Rommel SA, McLellan WA, Pabst DA, Costidis AM, Caron KM, Kernagis DN, Rotstein DS, Thayer VG, Harms CA, Piscitelli-Doshkov MA, Doshkov P, Schweikert LE, Yopak KE, Braun M, Tift MS.

Animals (Basel). 2025 Mar 4;15(5):729. doi: 10.3390/ani15050729.

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Misumi I, Yue Z, Jiang Z, Karampoori A, Whitmire JK, Cullen JM, Block T, Lemon SM, Du Y, Li Y.

Antiviral Res. 2025 Mar 19:106145. doi: 10.1016/j.antiviral.2025.106145. Online ahead of print.

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Anand JR, Droby GN, Joseph S, Patel U, Zhang X, Klomp JA, Der CJ, Purvis JE, Wolff SC, Bowser JL, Vaziri C.

NAR Cancer. 2025 Mar 20;7(1):zcaf009. doi: 10.1093/narcan/zcaf009. eCollection 2025 Mar.

�ʲѱ���:��40115747��Free PMC article.

Liu S, Corcoran DL, Garcia-Recio S, Marron JS, Perou CM.

NAR Genom Bioinform. 2025 Mar 19;7(1):lqaf023. doi: 10.1093/nargab/lqaf023. eCollection 2025 Mar.

�ʲѱ���:��40109353��Free PMC article.

Matentzoglu N, Bello SM, Stefancsik R, Alghamdi SM, Anagnostopoulos AV, Balhoff JP, Balk MA, Bradford YM, Bridges Y, Callahan TJ, Caufield H, Cuzick A, Carmody LC, Caron AR, de Souza V, Engel SR, Fey P, Fisher M, Gehrke S, Grove C, Hansen P, Harris NL, Harris MA, Harris L, Ibrahim A, Jacobsen JOB, Köhler S, McMurry JA, Munoz-Fuentes V, Munoz-Torres MC, Parkinson H, Pendlington ZM, Pilgrim C, Robb SMC, Robinson PN, Seager J, Segerdell E, Smedley D, Sollis E, Toro S, Vasilevsky N, Wood V, Haendel MA, Mungall CJ, McLaughlin JA, Osumi-Sutherland D.

Genetics. 2025 Mar 17;229(3):iyaf027. doi: 10.1093/genetics/iyaf027.

�ʲѱ���:��40048704��Free PMC article.

Hysong MR, Shuey MM, Huffman JE, Auer P, Reiner A, Raffield LM.

Blood Adv. 2025 Mar 25;9(6):1452-1462. doi: 10.1182/bloodadvances.2024014399.

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Trotman JB, Abrash EW, Murvin MM, Braceros AK, Li S, Boyson SP, Salcido RT, Cherney RE, Bischoff SR, Kaufmann K, Eberhard QE, Zhang Z, Cowley DO, Calabrese JM.

Mol Cell. 2025 Mar 20;85(6):1117-1133.e14. doi: 10.1016/j.molcel.2025.02.014.

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Wang JR, Alexander TB.

Front Oncol. 2025 Mar 6;15:1578509. doi: 10.3389/fonc.2025.1578509. eCollection 2025.

�ʲѱ���:��40115010��Free PMC article. No abstract available.

Wu JM, Siddiqui NY, Wiltshire T, Voora D, Schmader K.

Urogynecology (Phila). 2025 Feb 14. doi: 10.1097/SPV.0000000000001668. Online ahead of print.

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Salunke J, Byfield G, Powell SN, Torres DF, Leon-Lozano G, Jackson J, Orphanides AK, Shaw J, Owens T, Berg JS, Branch E, Caro L, Giric S, O’Daniel JM, Powell BC, Ray K, Robinson C, Schilling S, Shaw N, Song E, Waltz M, Roberts MC, Foreman AKM, Foss K, Milko LV.

Public Health Genomics. 2025;28(1):66-84. doi: 10.1159/000543227. Epub 2024 Dec 19.

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Demmer RT, Wu C, Kim JS, Sun Y, Balte P, Cushman M, Boyle R, Tracy RP, Styer LM, Bell TD, Anderson MR, Allen NB, Schreiner PJ, Bowler R, Schwartz DA, Lee JS, Xanthakis V, Rock JM, Bievenue R, Pirzada A, Doyle M, Regan EA, Make BJ, Kanaya AM, Kandula NR, Wenzel SE, Coresh J, Isasi CR, Raffield LM, Elkind MSV, Howard VJ, Ortega VE, Woodruff P, Cole SA, Henderson JM, Mantis NJ, Oelsner EC.

Open Forum Infect Dis. 2025 Mar 20;12(3):ofaf123. doi: 10.1093/ofid/ofaf123. eCollection 2025 Mar.

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Bridges Y, Souza V, Cortes KG, Haendel M, Harris NL, Korn DR, Marinakis NM, Matentzoglu N, McLaughlin JA, Mungall CJ, Odell A, Osumi-Sutherland D, Robinson PN, Smedley D, Jacobsen JOB.

BMC Bioinformatics. 2025 Mar 22;26(1):87. doi: 10.1186/s12859-025-06105-4.

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Georgakis MK, Malik R, Bounkari OE, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, Do R, Kenny EE, Loos RJF, Terry JG, Carr JJ, Bis JC, Psaty BM, Longstreth WT, Young KA, Lutz SM, Cho MH, Broome J, Khan AT, Wang FF, Heard-Costa N, Seshadri S, Vasan RS, Palmer ND, Freedman BI, Bowden DW, Yanek LR, Kral BG, Becker LC, Peyser PA, Bielak LF, Ammous F, Carson AP, Hall ME, Raffield LM, Rich SS, Post WS, Tracy RP, Taylor KD, Guo X, Mahaney MC, Curran JE, Blangero J, Clarke SL, Haessler JW, Hu Y, Assimes TL, Kooperberg C, Bernhagen J, Anderson CD, Damrauer SM, Zand R, Rotter JI, de Vries PS, Dichgans M.

Genome Med. 2025 Mar 21;17(1):27. doi: 10.1186/s13073-025-01456-2.

�ʲѱ���:��40119478��Free PMC article.

Yan H, Rini CM, Foreman AKM, Berg JS, Henderson GE, Lee K, O’Daniel JM, Roche M, Waltz M.

Per Med. 2025 Apr;22(2):93-101. doi: 10.1080/17410541.2025.2476392. Epub 2025 Mar 18.

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Balint L, Patel S, Serafin DS, Zhang H, Quinn KE, Aghajanian A, Kistner BM, Caron KM.

Arterioscler Thromb Vasc Biol. 2025 Mar 27. doi: 10.1161/ATVBAHA.124.322288. Online ahead of print.

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Geyer J, Opoku KB, Lin J, Ramkissoon L, Mullighan C, Bhakta N, Alexander TB, Wang JR.

Leukemia. 2025 Mar 24. doi: 10.1038/s41375-025-02565-y. Online ahead of print.

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