Research Interests
Keywords: Chromatin, epigenetics, transcription, cancer
We are interested in the links between epigenetics and gene regulation. Our primary focus is on understanding how changes to the composition of chromatin remodeling complexes are regulated, how their disruption affects their function, and contributes to disease. We focus on the SWI/SNF complex, which is mutated in 20% of all human tumors. This complex contains many variable subunits that can be assembled in combination to yield thousands of biochemically distinct complexes. We use a variety of computational and wet-lab techniques in cell culture and animal models to address these questions.
Mentor Training:
- Faculty Mentoring Workshop for Biomedical Researchers
Training Program Affiliations:
- Bioinformatics and Computational Biology
- Genetics and Molecular Biology
Publications
Jesse Raab in 黑料网 Genetics News
December 3, 2024
Department of Genetics Publications for November 10th – 23rd, 2024
Department of Genetics faculty, postdocs, students and collaborators published 19 papers during November 10th - 23rd, 2024.
June 3, 2024
NIGMS Diversity Supplement Awarded to Jackie Brinkman
A new supplement to the NIGMS R35 grant 聽鈥淢echanisms of SWI/SNF complex assembly and function鈥� 聽(Dr. Jesse Raab, PI) has been awarded to Jackie Brinkman, BS.
November 19, 2023
Department of Genetics Publications for November 5th – 18th, 2023
Department of Genetics faculty, postdocs, students and collaborators published 5 papers during November 5th - 18th 2023.
July 27, 2022
Jesse Raab, PhD Awarded R35 Grant from NIGMS
Dr. Jesse Raab (Assistant Professor, Department of Genetics) has been awarded a five-year R35 grant from the National Institute of General Medical Sciences (NIGMS) for his project titled 鈥淢echanisms of SWI/SNF complex assembly and function鈥�.
February 9, 2022
Katie Hoadley, PhD and Jesse Raab, PhD Receive CEHS Pilot Award
Drs. Katie Hoadley and Jesse Raab (Assistant Professors, Genetics) received a Team Science Pilot Project Award from the 黑料网 Center for Environmental Health and Susceptibility (CEHS) for their collaborative project titled 鈥淯nderstanding genetic and environmental drivers of primary liver cancer鈥�.聽
February 8, 2021
Department of Genetics Publications for Jan. 24 鈥� Feb. 6, 2021
Department of Genetics faculty, postdocs, students and collaborators published twenty papers during Jan. 24 鈥� Feb. 6, 2021.
January 4, 2021
Department of Genetics Publications for December 13-26, 2020
Department of Genetics faculty, postdocs, students and collaborators published nine papers during Dec. 13-26, 2020.
July 7, 2020
Jesse Raab, PhD Awarded Grant from Department of Defense (DOD)
Dr. Raab (Assistant Professor, Genetics) was awarded a grant from the U.S. Army Medical Research Acquisition Activity (USAMRAA) for his project titled 鈥淚dentification of New Therapeutic Strategies for Targeting Liver Fibrosis鈥�.聽
January 15, 2020
Department of Genetics Welcomes Dr. Jesse Raab
Jesse Raab, PhD has been appointed as Assistant Professor on the tenure-track, effective January 1, 2020.
January 6, 2020
Department of Genetics Publications for Dec. 15-28, 2019
Department of Genetics faculty, postdocs, students and collaborators published eleven documents during Dec. 15-28, 2019.