1.0Gene Therapy Center/genetherapyBetsy Clarke/genetherapy/author/bclarke/rich600338<blockquote class="wp-embedded-content" data-secret="TdBaAc5Tw5"><a href="/genetherapy/research-laboratories/hirsch-lab/">Hirsch Lab</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="/genetherapy/research-laboratories/hirsch-lab/embed/#?secret=TdBaAc5Tw5" width="600" height="338" title="“Hirsch Lab” — Gene Therapy Center" data-secret="TdBaAc5Tw5" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); /* ]]> */ </script> /genetherapy/wp-content/uploads/sites/811/2018/10/landingGraphic_hirsch.jpg2000900The Hirsch lab investigates the use adeno-associated viral (AAV) vectors for therapeutic gene delivery and gene editing towards the treatment of several genetic diseases. At the mechanistic level, we seek to characterize the cellular response to the multi-functional AAV inverted terminal repeats in gene addition and gene editing strategies. Our preclinical programs are targeted at … Read more