Biochemistry and biophysics PhD student, Cathy Spangler, researches in聽聽and recently published a paper in collaboration with Joshua Boyer, Joshua Strauss, Andrew Cesmat, Pengda Liu, Robert McGinty, and Qi Zhang, titled聽.听This article addresses the use of cryo-electron microscopy to determine the high-resolution structure of a DNA-sensing protein called cGAS聽bound to the nucleosome 鈥� the fundamental repeating unit of chromatin.