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X-WR-CALDESC:Events for Department of Cell Biology and Physiology
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DTSTART;TZID=America/New_York:20250331T123000
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CREATED:20250106T192312Z
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UID:10000437-1743424200-1743427800@www.med.unc.edu
SUMMARY:Monday - FUSION: Leo Bondel\, Katie Holmes\, & Jake Roetcisoender
DESCRIPTION:Leo Bondel (Zylka lab) \n\n\n\nOur goal is to identify guide RNAs targeting the UBE3A-ATS in human neurons\, which allow for installation of a Poly(A) signal with cytosine base editors\nThese edits have the potential to restore UBE3A expression\, making this an attractive therapeutic strategy for Angelman Syndrome\n\n\n\n  \n\n\n  \n\n\n \n\n\nKatie Holmes (Baldwin lab) \n\n\n\nWhite matter astrocytes maintain key astrocytic features like tiling and endfeet but their morphological characteristics are quantifiably distinct\nWhite matter astrocytes take longer to mature than other astrocytes\n\n\n\n  \n\n\n  \n\n\n \n\n\nJake Roetcisoender (O’Brien lab) \n\n\n\nVascular smooth muscle cells impact nerve development in the kidney\n\n\n\n 
URL:/cellbiophysio/event/14558/
LOCATION:G202 MBRB\, 111 Mason Farm Rd\, Chapel Hill
CATEGORIES:FUSION Seminar Series
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