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Spring 2025 Seminar Series – Sergiu Pasca, MD
April 14 @ 12:30 pm - 1:30 pm
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Kenneth T. Norris, Jr. Professor, Psychiatry & Behavioral Sciences
Stanford University
Research focus
Understanding human brain assembly and the molecular mechanisms that lead to neuropsychiatric disease using neural organoids
Faculty host
Trained as a physician in Romania, Dr. came for postdoctoral training at Stanford in 2009 where he developed some of the initial in vitro models of disease by deriving neurons from skin cells taken from patients with genetic brain disorders. His lab has afterwards introduced the use of instructive signals for reproducibly deriving self-organizing 3D cellular structures known as regionalized neural organoids or spheroids. To gain access to complex cellular interactions in the human brain, his research group also pioneered a modular system to study human neural circuits in preparations named assembloids.