{"id":7974,"date":"2025-03-19T08:44:17","date_gmt":"2025-03-19T12:44:17","guid":{"rendered":"https:\/\/www.med.unc.edu\/bric\/?page_id=7974"},"modified":"2025-04-22T09:46:15","modified_gmt":"2025-04-22T13:46:15","slug":"flat-panel-imaging","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/bric\/small-animal-imaging\/sai-equipment\/flat-panel-imaging\/","title":{"rendered":"Flat Panel Imaging"},"content":{"rendered":"<h3><strong>Instruments<\/strong><\/h3>\n<h4><em><br \/>\nSapphire Biomolecular Imager<\/em><\/h4>\n<p>The Sapphire Biomolecular Imager (Azure Biosystems Inc.) is a tabletop imaging system capable of providing near-infra-red (NIR) fluorescent imaging and phosphor imaging. It features a unique design where spectrally separated solid state lasers in combination with Avalanche Photodiodes (APD) are used to detect fluorescent signals. The system also integrates the Photomultiplier tube (PMT) for high gain amplification for phosphor imaging capability. The Sapphire Biomolecular imager has the following main features:<img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-7976 alignright\" src=\"https:\/\/www.med.unc.edu\/bric\/wp-content\/uploads\/sites\/843\/2025\/03\/Sapphire-Image.jpg\" alt=\"\" width=\"349\" height=\"331\" srcset=\"https:\/\/www.med.unc.edu\/bric\/wp-content\/uploads\/sites\/843\/2025\/03\/Sapphire-Image.jpg 349w, https:\/\/www.med.unc.edu\/bric\/wp-content\/uploads\/sites\/843\/2025\/03\/Sapphire-Image-300x285.jpg 300w\" sizes=\"auto, (max-width: 349px) 100vw, 349px\" \/><\/p>\n<p>Main Imaging Features<\/p>\n<ul>\n<li>Wide linear dynamic range: at least 5 orders of<br \/>\nmagnitude.<\/li>\n<li>High sensitivity: detecting at femtogram levels for fluorescent applications<\/li>\n<li>High Resolution: adjustable resolution from 1000 micron to 10 microns, making it ideal for scanning slides and arrays<\/li>\n<li>Two-channel NIR imaging capability: Two fluorescent solid-state laser diodes at 685 nm and 784 nm with 3nm narrow band<\/li>\n<li>Phosphor imaging capability: using laser light and PMT detector, providing high resolution imaging of phosphor screen at 25 um resolution.<\/li>\n<\/ul>\n<hr \/>\n<h3><strong style=\"color: inherit;font-size: 24px\">Sample Images and Study Examples<\/strong><\/h3>\n<p>To see sample images from our optical imaging systems please follow this<a href=\"https:\/\/www.med.unc.edu\/bric\/small-animal-imaging\/sai-equipment\/flat-panel-imaging\/flat-panel-imaging-sample-images\/\"> link<\/a>.<\/p>\n<hr \/>\n<h3><strong style=\"color: inherit;font-size: 24px\">Study Initiation, Training and Scheduling<\/strong><\/h3>\n<p>The SAI offers training on our Sapphire system so that users can conduct imaging themselves within our facility, please click on this <a href=\"https:\/\/www.med.unc.edu\/bric\/small-animal-imaging\/training\/#Optical_training\">link<\/a> to learn more.\u00a0 The Sapphire Biomolecular Imager can be scheduled after training by SAI staff through iLab.\u00a0 Staff supported imaging is also available upon request with additional fees.\u00a0 Please follow the instructions at the <a href=\"https:\/\/www.med.unc.edu\/bric\/small-animal-imaging\/schedule-a-study\/\">Schedule a Study<\/a> link for more details or contact us at <a href=\"mailto:bricsai@unc.edu\">bricsai@unc.edu<\/a> or call 919-966-2855 with questions.<\/p>\n<hr \/>\n<h3><strong>Cost<\/strong><\/h3>\n<p>The current internal rate for flat panel imaging is $58\/hr.\u00a0 Imaging time is highly dependent upon the study protocol so please contact the SAI for budget information. You can also see our <a href=\"https:\/\/www.med.unc.edu\/bric\/small-animal-imaging\/services\/copy_of_cost\/\">rates at this link<\/a>.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Instruments Sapphire Biomolecular Imager The Sapphire Biomolecular Imager (Azure Biosystems Inc.) is a tabletop imaging system capable of providing near-infra-red (NIR) fluorescent imaging and phosphor imaging. It features a unique design where spectrally separated solid state lasers in combination with Avalanche Photodiodes (APD) are used to detect fluorescent signals. The system also integrates the Photomultiplier &hellip; <a href=\"https:\/\/www.med.unc.edu\/bric\/small-animal-imaging\/sai-equipment\/flat-panel-imaging\/\" aria-label=\"Read more about Flat Panel Imaging\">Read more<\/a><\/p>\n","protected":false},"author":41912,"featured_media":0,"parent":2936,"menu_order":40,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-7974","page","type-page","status-publish","hentry","odd"],"pp_force_visibility":null,"pp_subpost_visibility":null,"pp_inherited_force_visibility":null,"pp_inherited_subpost_visibility":null,"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Flat Panel Imaging - Biomedical Research Imaging Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/bric\/small-animal-imaging\/sai-equipment\/flat-panel-imaging\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Flat Panel Imaging - Biomedical Research Imaging Center\" \/>\n<meta property=\"og:description\" content=\"Instruments Sapphire Biomolecular Imager The Sapphire Biomolecular Imager (Azure Biosystems Inc.) is a tabletop imaging system capable of providing near-infra-red (NIR) fluorescent imaging and phosphor imaging. 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