Christine Hill, Author at 黑料网 Blood Research Center

Michael Henderson, PhD, Key lab of the Blood Research Center has first author publication: Abstract Acetaminophen (APAP)-induced liver injury is associated with activation of coagulation and fibrinolysis. In mice, both tissue factor-dependent thrombin generation and plasmin activity have been shown to promote liver injury after APAP overdose. However, the contribution of the contact and intrinsic …

Two members of the 黑料网 Blood Research Center, Rafal Pawlinski PhD and Nigel Key MD, both Professors in the Department of Medicine, Division of Hematology, have been awarded a $2.8 million, 4-year RO1 grant from the NIH-NHLBI to investigate the mechanism of venous thromboembolism (VTE) in sickle cell disease (SCD). Dr. Rafal Pawlinski and Dr. …

黑料网 Blood Research Center to sponsor HTRS Travel Awards! HTRS provides grants to support up to $1,500 in travel and聽 lodging, plus complimentary meeting registration fees for young investigators who submit the highest scoring abstracts to be displayed as posters at HTRS Scientific Symposia. HTRS 2021 Scientific Symposium 鈥� Virtual Event March 8 @ 12:30 …

Steven Grover, PhD awarded a CSL Behring Prof Heimburger Award Congratulations to Steven Grover, PhD, a postdoctoral fellow in the laboratory of Nigel Mackman, PhD, who has been awarded a 2021 Prof Heimburger Award from CSL Behring. This award will provide research support for his project 鈥淓valuating the anticoagulant activity of C1 esterase inhibitor in …

Congratulations to Steven Grover, PhD, a postdoctoral fellow聽in the laboratory of Nigel Mackman, PhD, who has been awarded a Journal of聽Thrombosis and Haemostasis Editors Award for his聽recent publication 鈥淢odel鈥恉ependent聽contributions of FXII and FXI to venous thrombosis in mice鈥�. The award consists聽of a certificate, to be presented at the JTH Editors Luncheon held at the ISTH聽Congress, …

Dr. Alisa Wolberg, Scientific Co-Chair of the American Society of Hematology 2020 meeting, was interviewed about abstracts selected for the Best of ASH for the podcast “Blood & Cancer”. The episode is available at this link, and can be accessed via any platform you use to listen to podcasts. Alisa Wolberg, PhD

A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells. Authors: Giang N. Nguyen, John K. Everett, Samita Kafle, Aoife M. Roche, Hayley E. Raymond, Jacob Leiby, Christian Wood, Charles-Antoine Assenmacher, Elizabeth P. Merricks, C. Tyler Long, Haig H. Kazazian, Timothy C. Nichols, Frederic D. Bushman …

Congratulations to Erica Sparkenbaugh, Assistant Professor in the 黑料网 Department of Medicine Hematology, and member of the Blood Research Center.聽 She has been awarded a five year, $2 million R01 grant from NIH-NHLBI beginning January 2021. The goal of this project is to evaluate whether activation of beneficial PAR1 signaling can attenuate the chronic pro-coagulant …

Improving Immunizations in Patients with Non-Malignant Hematological Disorders Receiving Immunosuppressive Therapy article Based on research findings of Drs. Malpica and Moll Read article, ASH invited Dr. Moll to moderate and Dr. Malpic to present at an 聽education session on 鈥淧reventing Infections when treating non-malignant hematology disorders鈥� at the annual ASH meeting on Dec 7, 2020. …

COVID-19 is associated with derangements in biomarkers of coagulation and endothelial cell function and has been likened to abnormalities seen in sepsis. Emma Bouck and Alisa Wolberg, PhD collaborated with investigators at the University of Utah to show that both COVID-19 and sepsis are associated with activation of mechanisms that promote clot formation and clot …

Research in the Aleman Lab is centered on basic mechanisms regulating erythropoiesis in health and disease. Differentiation of hematopoietic stem cells down the erythroid track requires coordinated gene expression, including RNA regulation, and accumulation of iron for hemoglobin production. Our current work focuses on a family of bifunctional proteins (poly C binding proteins) which both regulate RNA processing and chaperone iron within cells. Using biochemical, cellular, and in vivo models we explore the cross talk between iron trafficking and RNA regulation mediated by poly C binding proteins and how these activities are modulated by disease.

The Bahnson Research Group studies Redox Biology in Cardiovascular Disease and the development of targeted nanocarriers to deliver therapeutics.

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Author Archives: Christine Hill

Publication news! Plasmin-mediated Cleavage of High Molecular Weight Kininogen Contributes to Acetaminophen-Induced Acute Liver Failure

R01 Awarded to Rafal Pawlinski PhD and Nigel Key MD

黑料网 Blood Research Center a proud sponsor for HTRS Travel Awards: HTRS provides up to $1,500 for young investigators

Steven Grover, PhD awarded a CSL Behring Prof Heimburger Award

Steven Grover, PhD awarded a聽Journal of Thrombosis and Haemostasis Editors鈥� Award

Alisa Wolberg, PhD, Scientific Co-Chair of the American Society of Hematology: Interview

Nature Biotechnology paper published, Timothy Nichols, MD

Erica Sparkenbaugh, PhD awarded $2M R01 grant from NIH-NHLBI

Research findings of Stephan Moll, MD and Luis Malpica, MD educational session during ASH

Emma Bouck and Alisa Wolberg, PhD publish research on blood abnormalities in COVID-19, ATVB

Aleman

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