黑料网

Research: Systems cancer biology and immunology, cancer therapeutic response, protein-protein interaction networks (interactomes), post-translational modifications, epigenetic regulation, signal transduction, disease marker discovery.

Xian Chen

Professor of Biochemistry and Biophysics
Faculty Director, Quantitative Proteomics Center for Disease Marker Discovery
(PhD 鈥� Penn State University)

Xian Chen is a Professor at the Department of Biochemistry and Biophysics at 黑料网-CH, Faculty Director for 黑料网-Duke Michael Hooker Proteomics Center, and a member of Lineberger NCI Comprehensive Cancer Center. He completed his B.S. undergraduate degree in Chemistry for Peking (Beijing) University, China. He then came to US to obtain his Ph.D. in Physical Organic Chemistry from the Penn State University. Followed by a two-year postdoctoral training in the field of molecular biology and enzymology at University of Florida Health Science Center, he joined Life Science Division, Los Alamos National Lab, first as a postdoctoral fellow studying in multi-dimensional structures of DNA and proteins primarily using NMR, later he became a staff member and then was promoted to the Leader of a bioanalytical team. He joined the 黑料网-Chapel Hill faculty in late 2006.聽 Because of his multi-disciplinary training background, Dr. Chen has broad research interests cross biochemistry, biophysics, genetics, and biology, with an emphasis on studies of systems dysregulation of cellular signaling and functional pathways in diseases. His research group in conjunction with the technology development mission at the Proteomics Center also focus on developing novel techniques capable of performing systems investigation to address 鈥榬eal-world鈥� biological concerns in more sensitive, precise, and high throughput way.